Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(antitoxin)
Location 1215155..1215660 Replicon chromosome
Accession NZ_CP098805
Organism Dyadobacter chenhuakuii strain CY22

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NFI80_RS05015 Protein ID WP_235164680.1
Coordinates 1215155..1215346 (+) Length 64 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NFI80_RS05020 Protein ID WP_235165097.1
Coordinates 1215343..1215660 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFI80_RS05000 (NFI80_04995) 1210460..1212430 - 1971 WP_235164682.1 TonB-dependent receptor plug domain-containing protein -
NFI80_RS05005 (NFI80_05000) 1212478..1212798 - 321 WP_233798060.1 hypothetical protein -
NFI80_RS05010 (NFI80_05005) 1212818..1214890 - 2073 WP_235164681.1 heavy metal translocating P-type ATPase -
NFI80_RS05015 (NFI80_05010) 1215155..1215346 + 192 WP_235164680.1 hypothetical protein Toxin
NFI80_RS05020 (NFI80_05015) 1215343..1215660 + 318 WP_235165097.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
NFI80_RS05025 (NFI80_05020) 1215875..1216330 + 456 WP_235164679.1 DUF1572 family protein -
NFI80_RS05030 (NFI80_05025) 1216386..1217789 + 1404 WP_235164678.1 pyridoxal-dependent decarboxylase -
NFI80_RS05035 (NFI80_05030) 1217786..1219894 - 2109 WP_235164677.1 metallophosphoesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

mRNA interferase PemK-like

(1-104)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7223.91 Da        Isoelectric Point: 3.6568

>T248103 WP_235164680.1 NZ_CP098805:1215155-1215346 [Dyadobacter chenhuakuii]
MMEQCDIKDLVNVEVKGNSIVIEPATQSPRAGWEQQFELANKGSEEDLMEGFSNEFDDAEWTW

Download         Length: 192 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11465.53 Da        Isoelectric Point: 9.9469

>AT248103 WP_235165097.1 NZ_CP098805:1215343-1215660 [Dyadobacter chenhuakuii]
VIKRFEIYLVSLDPTVGSEIKKSRPCVVISPDEVNRSLNTVIIAPLTSTIKKYPTRIACSVANKAGQIALDQLRTVDKVR
LSKKIGILDAETSEGVLDILKALFA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References