Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 619137..619672 Replicon plasmid pRA_T24_2
Accession NZ_CP098804
Organism Rhizobium anhuiense bv. trifolii strain T24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NE851_RS34605 Protein ID WP_097543725.1
Coordinates 619397..619672 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3S0SSF2
Locus tag NE851_RS34600 Protein ID WP_047618843.1
Coordinates 619137..619397 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE851_RS34575 (NE851_34540) 614380..615198 - 819 WP_029733067.1 ABC transporter ATP-binding protein -
NE851_RS34580 (NE851_34545) 615295..616308 - 1014 WP_029733068.1 ABC transporter substrate-binding protein -
NE851_RS34585 (NE851_34550) 616420..617418 - 999 Protein_546 helix-turn-helix domain-containing protein -
NE851_RS34590 (NE851_34555) 617415..617993 - 579 WP_179867830.1 isochorismatase family protein -
NE851_RS34595 (NE851_34560) 618117..618845 - 729 WP_097543806.1 FadR/GntR family transcriptional regulator -
NE851_RS34600 (NE851_34565) 619137..619397 + 261 WP_047618843.1 ribbon-helix-helix domain-containing protein Antitoxin
NE851_RS34605 (NE851_34570) 619397..619672 + 276 WP_097543725.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NE851_RS34610 (NE851_34575) 619679..620686 - 1008 WP_097543726.1 LacI family DNA-binding transcriptional regulator -
NE851_RS34615 (NE851_34580) 620893..622215 + 1323 WP_097543727.1 alpha-L-fucosidase -
NE851_RS34620 (NE851_34585) 622266..623486 + 1221 WP_097543728.1 sugar ABC transporter substrate-binding protein -
NE851_RS34625 (NE851_34590) 623522..624448 + 927 WP_097543729.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..767332 767332


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10848.40 Da        Isoelectric Point: 9.9696

>T248102 WP_097543725.1 NZ_CP098804:619397-619672 [Rhizobium anhuiense bv. trifolii]
MEVKWTSKAVSDVTRLYDFLSPVDRRAAARTVQALTAAPARLLEQSRLGERLEEFDPREVRRILVGRYELRYEIQQSTIY
VLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9684.91 Da        Isoelectric Point: 4.6135

>AT248102 WP_047618843.1 NZ_CP098804:619137-619397 [Rhizobium anhuiense bv. trifolii]
METKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDSGNVVDHQAVQAWADSLDSDE
PISLPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3S0SSF2

References