Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 430727..431397 Replicon plasmid pRA_T24_1
Accession NZ_CP098801
Organism Rhizobium anhuiense bv. trifolii strain T24

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NE851_RS02145 Protein ID WP_097544206.1
Coordinates 430978..431397 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NE851_RS02140 Protein ID WP_097544240.1
Coordinates 430727..430981 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE851_RS02120 (NE851_02110) 425924..426550 - 627 WP_028757558.1 pyridoxamine 5'-phosphate oxidase family protein -
NE851_RS02125 (NE851_02115) 426650..427624 - 975 WP_097544204.1 alpha/beta hydrolase -
NE851_RS02130 (NE851_02120) 428056..429963 + 1908 WP_097544205.1 PAS domain S-box protein -
NE851_RS02135 (NE851_02125) 429953..430576 + 624 WP_028757555.1 response regulator -
NE851_RS02140 (NE851_02130) 430727..430981 + 255 WP_097544240.1 plasmid stabilization protein Antitoxin
NE851_RS02145 (NE851_02135) 430978..431397 + 420 WP_097544206.1 type II toxin-antitoxin system VapC family toxin Toxin
NE851_RS02150 (NE851_02140) 431482..432315 - 834 WP_097544241.1 AraC family transcriptional regulator -
NE851_RS02155 (NE851_02145) 432608..433513 + 906 WP_245433438.1 AraC family transcriptional regulator -
NE851_RS02160 (NE851_02150) 433646..434626 - 981 WP_097544207.1 alpha/beta hydrolase -
NE851_RS02165 (NE851_02155) 434694..436292 - 1599 WP_097544208.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1441560 1441560


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15213.53 Da        Isoelectric Point: 5.7251

>T248101 WP_097544206.1 NZ_CP098801:430978-431397 [Rhizobium anhuiense bv. trifolii]
MILLDTNVLSEPWKPAPDERVVAWLDAQAIETLFLSVMTIAELRFGIAAMPLGKRQTILHDRLEGEVLPHFSERILSFNL
ASSQFYSELMVRARVSGRTIGTSDGYIAATAAANGLAVATRDTSPFEAAGLKVINPWAR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9234.38 Da        Isoelectric Point: 5.6228

>AT248101 WP_097544240.1 NZ_CP098801:430727-430981 [Rhizobium anhuiense bv. trifolii]
VPAVTIRNLSDETHRALRVRAAHHGRSTEAEIRDIIEAAVRPSERVKLGSLLAAIGREAELSNLDVEALQNNRDDTPAVP
MPFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References