Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 321015..321814 Replicon plasmid pRA_T24_1
Accession NZ_CP098801
Organism Rhizobium anhuiense bv. trifolii strain T24

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NE851_RS01575 Protein ID WP_254955871.1
Coordinates 321311..321814 (+) Length 168 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NE851_RS01570 Protein ID WP_097623327.1
Coordinates 321015..321314 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE851_RS01555 (NE851_01550) 316932..318299 - 1368 WP_097623324.1 metallophosphoesterase -
NE851_RS01560 (NE851_01555) 318296..319609 - 1314 WP_097623325.1 protein kinase -
NE851_RS01565 (NE851_01560) 319627..320523 - 897 WP_097623326.1 vWA domain-containing protein -
NE851_RS01570 (NE851_01565) 321015..321314 + 300 WP_097623327.1 DUF1778 domain-containing protein Antitoxin
NE851_RS01575 (NE851_01570) 321311..321814 + 504 WP_254955871.1 GNAT family N-acetyltransferase Toxin
NE851_RS01580 (NE851_01575) 322246..322755 - 510 WP_097623329.1 hypothetical protein -
NE851_RS01585 (NE851_01580) 322977..323279 + 303 WP_097623330.1 hypothetical protein -
NE851_RS01590 (NE851_01585) 323741..323932 + 192 WP_143541139.1 IS66 family insertion sequence element accessory protein TnpB -
NE851_RS01595 (NE851_01590) 324295..324489 - 195 WP_097623331.1 hypothetical protein -
NE851_RS01600 (NE851_01595) 324616..324946 + 331 Protein_319 terminase small subunit protein -
NE851_RS01605 (NE851_01600) 325142..325882 + 741 WP_245445217.1 TIM barrel protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1441560 1441560
- flank IS/Tn - - 323741..323932 191


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-142)

Antitoxin

Vibrio phage ICP1, Orf50

(13-98)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18167.74 Da        Isoelectric Point: 9.6204

>T248100 WP_254955871.1 NZ_CP098801:321311-321814 [Rhizobium anhuiense bv. trifolii]
VTLSAPIPLADHHELSEFNSSVPELNDWLRRRARANQVGGASRTFVVCEENRVIAYYALASGAVKQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSYQGRGIGRALVRDAGLRLLNAAEILGIRGVFVHAISNDARAFYQAVGFLPSPSDPMMRMVGLNDFS
SALNSQP

Download         Length: 504 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11272.84 Da        Isoelectric Point: 5.8769

>AT248100 WP_097623327.1 NZ_CP098801:321015-321314 [Rhizobium anhuiense bv. trifolii]
MPTTSHTSISPDASVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTIFTVSPEIYAEYLARLDVPT
QPNERLRRTMSTKAPWDEA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References