Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3280809..3281462 Replicon chromosome
Accession NZ_CP098795
Organism Acinetobacter baumannii strain VB280821

Toxin (Protein)


Gene name cptA Uniprot ID A0A3R9G864
Locus tag NE424_RS15875 Protein ID WP_000607075.1
Coordinates 3281073..3281462 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NE424_RS15870 Protein ID WP_001288210.1
Coordinates 3280809..3281066 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE424_RS15850 (NE424_15850) 3276325..3277332 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
NE424_RS15855 (NE424_15855) 3277351..3277728 + 378 WP_001216380.1 50S ribosomal protein L17 -
NE424_RS15860 (NE424_15860) 3277910..3279400 + 1491 WP_031966421.1 NAD(P)/FAD-dependent oxidoreductase -
NE424_RS15865 (NE424_15865) 3279449..3280621 - 1173 WP_032028213.1 acyl-CoA dehydrogenase family protein -
NE424_RS15870 (NE424_15870) 3280809..3281066 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
NE424_RS15875 (NE424_15875) 3281073..3281462 + 390 WP_000607075.1 membrane protein Toxin
NE424_RS15880 (NE424_15880) 3282232..3283317 + 1086 WP_000049106.1 hypothetical protein -
NE424_RS15885 (NE424_15885) 3283395..3283961 + 567 WP_000651536.1 rhombosortase -
NE424_RS15890 (NE424_15890) 3284149..3286344 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.94 Da        Isoelectric Point: 10.3890

>T248094 WP_000607075.1 NZ_CP098795:3281073-3281462 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKVIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT248094 WP_001288210.1 NZ_CP098795:3280809-3281066 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3R9G864

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References