Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3670205..3670858 Replicon chromosome
Accession NZ_CP098791
Organism Acinetobacter baumannii strain 280820

Toxin (Protein)


Gene name cptA Uniprot ID A0A3R9G864
Locus tag NE421_RS17395 Protein ID WP_000607075.1
Coordinates 3670205..3670594 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NE421_RS17400 Protein ID WP_001288210.1
Coordinates 3670601..3670858 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE421_RS17380 (NE421_17380) 3665323..3667518 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
NE421_RS17385 (NE421_17385) 3667706..3668272 - 567 WP_000651536.1 rhombosortase -
NE421_RS17390 (NE421_17390) 3668350..3669435 - 1086 WP_000049106.1 hypothetical protein -
NE421_RS17395 (NE421_17395) 3670205..3670594 - 390 WP_000607075.1 membrane protein Toxin
NE421_RS17400 (NE421_17400) 3670601..3670858 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
NE421_RS17405 (NE421_17405) 3671046..3672218 + 1173 WP_032028213.1 acyl-CoA dehydrogenase family protein -
NE421_RS17410 (NE421_17410) 3672267..3673757 - 1491 WP_031966421.1 NAD(P)/FAD-dependent oxidoreductase -
NE421_RS17415 (NE421_17415) 3673939..3674316 - 378 WP_001216380.1 50S ribosomal protein L17 -
NE421_RS17420 (NE421_17420) 3674335..3675342 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.94 Da        Isoelectric Point: 10.3890

>T248090 WP_000607075.1 NZ_CP098791:c3670594-3670205 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKVIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT248090 WP_001288210.1 NZ_CP098791:c3670858-3670601 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3R9G864

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References