Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3686357..3687014 Replicon chromosome
Accession NZ_CP098778
Organism Enterobacter hormaechei strain YQ13422hy

Toxin (Protein)


Gene name cptA Uniprot ID A0A179PSF7
Locus tag ND013_RS17605 Protein ID WP_017382887.1
Coordinates 3686357..3686767 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag ND013_RS17610 Protein ID WP_003863437.1
Coordinates 3686748..3687014 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND013_RS17585 3682355..3684088 - 1734 WP_017382886.1 single-stranded-DNA-specific exonuclease RecJ -
ND013_RS17590 3684094..3684807 - 714 WP_023295380.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND013_RS17595 3684836..3685732 - 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
ND013_RS17600 3685834..3686355 + 522 WP_015571793.1 flavodoxin FldB -
ND013_RS17605 3686357..3686767 - 411 WP_017382887.1 protein YgfX Toxin
ND013_RS17610 3686748..3687014 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
ND013_RS17615 3687309..3688289 + 981 WP_022649306.1 tRNA-modifying protein YgfZ -
ND013_RS17620 3688401..3689060 - 660 WP_003863433.1 hemolysin III family protein -
ND013_RS17625 3689327..3690058 + 732 WP_015571796.1 MurR/RpiR family transcriptional regulator -
ND013_RS17630 3690175..3691608 + 1434 WP_017382891.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T248086 WP_017382887.1 NZ_CP098778:c3686767-3686357 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT248086 WP_003863437.1 NZ_CP098778:c3687014-3686748 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A179PSF7

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References