Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 106735..107454 Replicon chromosome
Accession NZ_CP098778
Organism Enterobacter hormaechei strain YQ13422hy

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag ND013_RS00525 Protein ID WP_126498987.1
Coordinates 106735..107055 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag ND013_RS00530 Protein ID WP_125372192.1
Coordinates 107089..107454 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND013_RS00505 102338..102679 - 342 WP_006812446.1 SymE family type I addiction module toxin -
ND013_RS00510 102816..102992 + 177 WP_072052037.1 toxin-antitoxin system HicB family antitoxin -
ND013_RS00515 103274..105241 - 1968 WP_220719616.1 antiviral reverse transcriptase Drt3b -
ND013_RS00520 105242..106495 - 1254 WP_126314420.1 antiviral reverse transcriptase Drt3a -
ND013_RS00525 106735..107055 - 321 WP_126498987.1 TA system toxin CbtA family protein Toxin
ND013_RS00530 107089..107454 - 366 WP_125372192.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
ND013_RS00535 107466..107708 - 243 WP_126498988.1 DUF987 domain-containing protein -
ND013_RS00540 107717..108187 - 471 WP_126498989.1 DNA repair protein RadC -
ND013_RS00545 108257..109078 - 822 WP_126498990.1 DUF932 domain-containing protein -
ND013_RS00550 109771..110610 - 840 WP_126498991.1 hypothetical protein -
ND013_RS00555 110723..111157 - 435 WP_126498992.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 96624..128483 31859


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-104)

Antitoxin

Antitoxin CbeA

(18-116)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12156.75 Da        Isoelectric Point: 5.9559

>T248075 WP_126498987.1 NZ_CP098778:c107055-106735 [Enterobacter hormaechei]
MHISTVPATVTVSSRLSPVQVWQKLLTYILEHHYGLTINDTPFSNDTTIQEHIEAGVNLTDAVNFLVERFELVRIDQKGL
SWQDQEPWITSLDVHRAQFNLGLKRS

Download         Length: 321 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13442.17 Da        Isoelectric Point: 6.8421

>AT248075 WP_125372192.1 NZ_CP098778:c107454-107089 [Enterobacter hormaechei]
MQSTTLSGTSAENASCLQWGLKRNITPCFGARLVQEGNRLYFLADRAGFNGSFSDDEALRLDQAFPLMMKQLERMLTAGE
LDPRSQHCVTRHHNGLTCEADTLGSHGYVYIAIYPQSALTR

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References