248071

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3678351..3678870 Replicon chromosome
Accession NZ_CP098777
Organism Cronobacter sakazakii strain JXES-28

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NES82_RS17880 Protein ID WP_004385271.1
Coordinates 3678351..3678638 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NES82_RS17885 Protein ID WP_105579789.1
Coordinates 3678628..3678870 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NES82_RS17860 (NES82_17865) 3673433..3673963 - 531 WP_105608413.1 NAD(P)H-dependent oxidoreductase -
NES82_RS17865 (NES82_17870) 3674066..3674947 + 882 WP_161574629.1 LysR family transcriptional regulator -
NES82_RS17870 (NES82_17875) 3675244..3677379 + 2136 WP_105944704.1 anaerobic ribonucleoside-triphosphate reductase -
NES82_RS17875 (NES82_17880) 3677879..3678343 + 465 WP_007897806.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NES82_RS17880 (NES82_17885) 3678351..3678638 - 288 WP_004385271.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NES82_RS17885 (NES82_17890) 3678628..3678870 - 243 WP_105579789.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NES82_RS17890 (NES82_17895) 3678948..3680858 - 1911 WP_161574630.1 PRD domain-containing protein -
NES82_RS17895 (NES82_17900) 3680972..3681712 - 741 WP_161574631.1 KDGP aldolase family protein -
NES82_RS17900 (NES82_17905) 3681709..3682827 - 1119 WP_161574632.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10811.80 Da        Isoelectric Point: 10.5836

>T248071 WP_004385271.1 NZ_CP098777:c3678638-3678351 [Cronobacter sakazakii]
MSYKLVFDPRALKEWHKLGETVKAQFKKKLAHVLAAPRVKSARLSGLPDCYKIKLRTSGYRLVYQVRDDAVCVLVIAIGK
RENLTVYQGAGHRLE

Download         Length: 288 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9023.42 Da        Isoelectric Point: 4.7863

>AT248071 WP_105579789.1 NZ_CP098777:c3678870-3678628 [Cronobacter sakazakii]
MATINVRLDDKLKNEAYAVLEKLGITPTEAVRLLFQYVAQNGRMPVKTLTVSDSEEALLRTVRERLADPQPGIRVELDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References