Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2391771..2392330 Replicon chromosome
Accession NZ_CP098774
Organism Sphingomonas sp. QA11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NDN01_RS11160 Protein ID WP_272627447.1
Coordinates 2391771..2392064 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NDN01_RS11165 Protein ID WP_272627448.1
Coordinates 2392061..2392330 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDN01_RS11130 (NDN01_11100) 2388485..2388817 - 333 WP_272627443.1 hypothetical protein -
NDN01_RS11135 (NDN01_11105) 2388810..2389553 - 744 WP_272627444.1 queuosine precursor transporter -
NDN01_RS11145 (NDN01_11115) 2389671..2391371 - 1701 WP_272628167.1 recombinase family protein -
NDN01_RS11150 (NDN01_11120) 2391380..2391619 - 240 WP_272627445.1 hypothetical protein -
NDN01_RS11155 2391635..2391766 - 132 WP_272627446.1 hypothetical protein -
NDN01_RS11160 (NDN01_11125) 2391771..2392064 - 294 WP_272627447.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NDN01_RS11165 (NDN01_11130) 2392061..2392330 - 270 WP_272627448.1 ribbon-helix-helix domain-containing protein Antitoxin
NDN01_RS11170 (NDN01_11135) 2393001..2393315 + 315 Protein_2210 ParB/Srx family N-terminal domain-containing protein -
NDN01_RS11175 (NDN01_11140) 2393602..2393775 - 174 WP_272627449.1 hypothetical protein -
NDN01_RS11180 (NDN01_11145) 2393807..2394691 - 885 WP_272627450.1 hypothetical protein -
NDN01_RS11185 (NDN01_11150) 2394703..2395617 - 915 WP_272627451.1 arginase family protein -
NDN01_RS11190 (NDN01_11155) 2395804..2396676 + 873 WP_272627452.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11440.11 Da        Isoelectric Point: 9.5030

>T248058 WP_272627447.1 NZ_CP098774:c2392064-2391771 [Sphingomonas sp. QA11]
MRIKWTSKASSDLVRLHEHLQPVAPDAAARVVQQLARAPDRLLDYPRIGEKLEAYEPREVRRIIVGNYELRYEIADATIF
ILRLWHARENRSFKSEE

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9766.08 Da        Isoelectric Point: 4.8087

>AT248058 WP_272627448.1 NZ_CP098774:c2392330-2392061 [Sphingomonas sp. QA11]
MATDTKVLTAHVPLGLAEKVEAMAARLERSRGWVMKQALAAWVDQEEERHQMTLEALDDVDAGRVIDHHAVQAWADSLGT
DKPLPPPTA

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References