Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5172176..5172321 Replicon chromosome
Accession NZ_CP098758
Organism Klebsiella pneumoniae strain KP167

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5172183..5172285 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5172176..5172321 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND678_RS25075 5167708..5169141 + 1434 WP_252109906.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ND678_RS25080 5169257..5169496 + 240 WP_002911393.1 YebV family protein -
ND678_RS25085 5169594..5169785 + 192 WP_002911395.1 YebW family protein -
ND678_RS25090 5169782..5170435 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
ND678_RS25095 5170592..5171560 + 969 WP_014907334.1 VirK/YbjX family protein -
ND678_RS25100 5171665..5171808 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5172176..5172321 + 146 - - Antitoxin
- 5172183..5172285 - 103 - - Toxin
ND678_RS25105 5172444..5172782 - 339 WP_002911404.1 YebY family protein -
ND678_RS25110 5172799..5173668 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ND678_RS25115 5173672..5174046 - 375 WP_020316569.1 CopC domain-containing protein YobA -
ND678_RS25120 5174159..5174389 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ND678_RS25125 5174468..5175127 + 660 WP_002911407.1 exodeoxyribonuclease X -
ND678_RS25130 5175131..5177191 - 2061 WP_032419805.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T248015 NZ_CP098758:c5172285-5172183 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT248015 NZ_CP098758:5172176-5172321 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References