247999

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 2757567..2758386 Replicon chromosome
Accession NZ_CP098757
Organism Klebsiella oxytoca strain AHC-6

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag NDX50_RS13010 Protein ID WP_004110819.1
Coordinates 2757567..2757824 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag NDX50_RS13015 Protein ID WP_064398595.1
Coordinates 2757835..2758386 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDX50_RS12995 (NDX50_12985) 2753339..2754115 - 777 WP_004099223.1 Uxu operon transcriptional regulator -
NDX50_RS13000 (NDX50_12990) 2754251..2755726 - 1476 WP_047720344.1 fructuronate reductase -
NDX50_RS13005 (NDX50_12995) 2755801..2756985 - 1185 WP_004099225.1 mannonate dehydratase -
NDX50_RS13010 (NDX50_13000) 2757567..2757824 + 258 WP_004110819.1 YjhX family toxin Toxin
NDX50_RS13015 (NDX50_13005) 2757835..2758386 + 552 WP_064398595.1 N-acetyltransferase Antitoxin
NDX50_RS13020 (NDX50_13010) 2758500..2758874 + 375 Protein_2528 class I SAM-dependent methyltransferase -
NDX50_RS13025 (NDX50_13015) 2759268..2760032 + 765 WP_224314054.1 class I SAM-dependent methyltransferase -
NDX50_RS13030 (NDX50_13020) 2760078..2761241 - 1164 WP_024273763.1 MFS transporter -
NDX50_RS13035 (NDX50_13025) 2761259..2762536 - 1278 WP_064398600.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-130)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T247999 WP_004110819.1 NZ_CP098757:2757567-2757824 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20094.97 Da        Isoelectric Point: 7.0633

>AT247999 WP_064398595.1 NZ_CP098757:2757835-2758386 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVAALLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGVSDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHAAYYPRHGFDPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References