Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 2757567..2758386 Replicon chromosome
Accession NZ_CP098757
Organism Klebsiella oxytoca strain AHC-6

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag NDX50_RS13010 Protein ID WP_004110819.1
Coordinates 2757567..2757824 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag NDX50_RS13015 Protein ID WP_064398595.1
Coordinates 2757835..2758386 (+) Length 184 a.a.

Genomic Context


NDX50_RS13010NDX50_RS13015NDX50_RS13020NDX50_RS13025NDX50_RS12995NDX50_RS13000NDX50_RS13005NDX50_RS13030NDX50_RS13035
Location: 2757567..2757824 (258 bp)
Type: Toxin
Protein ID: WP_004110819.1
Location: 2757835..2758386 (552 bp)
Type: Antitoxin
Protein ID: WP_064398595.1
Location: 2758500..2758874 (375 bp)
Type: Others
Protein ID: Protein_2528
Location: 2759268..2760032 (765 bp)
Type: Others
Protein ID: WP_224314054.1
Location: 2753339..2754115 (777 bp)
Type: Others
Protein ID: WP_004099223.1
Location: 2754251..2755726 (1476 bp)
Type: Others
Protein ID: WP_047720344.1
Location: 2755801..2756985 (1185 bp)
Type: Others
Protein ID: WP_004099225.1
Location: 2760078..2761241 (1164 bp)
Type: Others
Protein ID: WP_024273763.1
Location: 2761259..2762536 (1278 bp)
Type: Others
Protein ID: WP_064398600.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NDX50_RS12995 (NDX50_12985)2753339..2754115-777WP_004099223.1Uxu operon transcriptional regulator-
NDX50_RS13000 (NDX50_12990)2754251..2755726-1476WP_047720344.1fructuronate reductase-
NDX50_RS13005 (NDX50_12995)2755801..2756985-1185WP_004099225.1mannonate dehydratase-
NDX50_RS13010 (NDX50_13000)2757567..2757824+258WP_004110819.1YjhX family toxinToxin
NDX50_RS13015 (NDX50_13005)2757835..2758386+552WP_064398595.1N-acetyltransferaseAntitoxin
NDX50_RS13020 (NDX50_13010)2758500..2758874+375Protein_2528class I SAM-dependent methyltransferase-
NDX50_RS13025 (NDX50_13015)2759268..2760032+765WP_224314054.1class I SAM-dependent methyltransferase-
NDX50_RS13030 (NDX50_13020)2760078..2761241-1164WP_024273763.1MFS transporter-
NDX50_RS13035 (NDX50_13025)2761259..2762536-1278WP_064398600.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-85)

Antitoxin

(17-130)


Sequences


Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T247999 WP_004110819.1 NZ_CP098757:2757567-2757824 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp


Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20094.97 Da        Isoelectric Point: 7.0633

>AT247999 WP_064398595.1 NZ_CP098757:2757835-2758386 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVAALLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGVSDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHAAYYPRHGFDPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A0H3H6Y2


Antitoxin

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Source
ID
Structure
No matching records found

References