247941

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT_toxin-BrnA
Location 2743459..2743909 Replicon chromosome
Accession NZ_CP098736
Organism Cupriavidus gilardii strain QJ1

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag NDR89_RS22575 Protein ID WP_232963065.1
Coordinates 2743459..2743572 (+) Length 38 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag NDR89_RS22580 Protein ID WP_252252901.1
Coordinates 2743556..2743909 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDR89_RS22560 (NDR89_22560) 2739632..2740339 - 708 WP_252252899.1 two-component system response regulator CreB -
NDR89_RS22565 (NDR89_22565) 2740394..2741602 - 1209 WP_252252900.1 NAD(P)/FAD-dependent oxidoreductase -
NDR89_RS22570 (NDR89_22570) 2742077..2743258 + 1182 WP_198751423.1 benzoate/H(+) symporter BenE family transporter -
NDR89_RS22575 (NDR89_22575) 2743459..2743572 + 114 WP_232963065.1 hypothetical protein Toxin
NDR89_RS22580 (NDR89_22580) 2743556..2743909 + 354 WP_252252901.1 BrnA antitoxin family protein Antitoxin
NDR89_RS22585 (NDR89_22585) 2743917..2744777 + 861 WP_252252902.1 aminoglycoside 6-adenylyltransferase -
NDR89_RS22590 (NDR89_22590) 2744904..2745599 - 696 WP_252252903.1 TrkA family potassium uptake protein -
NDR89_RS22595 (NDR89_22595) 2745592..2746920 - 1329 WP_053821273.1 potassium transporter TrkG -
NDR89_RS22600 (NDR89_22600) 2747305..2747736 + 432 WP_053821272.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(27-107)


Sequences

Toxin        


Download         Length: 38 a.a.        Molecular weight: 4405.10 Da        Isoelectric Point: 9.2738

>T247941 WP_232963065.1 NZ_CP098736:2743459-2743572 [Cupriavidus gilardii]
IGTRLHCLIFTIRGDTLRAISLRKANFREVRDYEQEI

Download         Length: 114 bp

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 12988.94 Da        Isoelectric Point: 10.6742

>AT247941 WP_252252901.1 NZ_CP098736:2743556-2743909 [Cupriavidus gilardii]
MNRKSKLTMPAADENAAIARGIADDPDAVELTTEQIKRMRPAREALAEVLGERNVEALIKRRGRPALPAAERKVSQTLRL
DPDVLQAFKATGDGWQTRINDALRAYAKSHRMLPRGC

Download         Length: 354 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References