247938

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 178589..179193 Replicon chromosome
Accession NZ_CP098735
Organism Cupriavidus gilardii strain QJ1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NDR89_RS00745 Protein ID WP_174780282.1
Coordinates 178888..179193 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NDR89_RS00740 Protein ID WP_082371731.1
Coordinates 178589..178891 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDR89_RS00715 (NDR89_00715) 173859..174836 - 978 WP_053823860.1 tripartite tricarboxylate transporter substrate binding protein -
NDR89_RS00720 (NDR89_00720) 175066..175809 + 744 WP_053823861.1 GntR family transcriptional regulator -
NDR89_RS00725 (NDR89_00725) 175869..176240 + 372 WP_053823862.1 cupin domain-containing protein -
NDR89_RS00730 (NDR89_00730) 176362..177120 + 759 WP_064575370.1 glucose 1-dehydrogenase -
NDR89_RS00735 (NDR89_00735) 177229..178557 + 1329 WP_006577627.1 MFS transporter -
NDR89_RS00740 (NDR89_00740) 178589..178891 - 303 WP_082371731.1 putative addiction module antidote protein Antitoxin
NDR89_RS00745 (NDR89_00745) 178888..179193 - 306 WP_174780282.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NDR89_RS00750 (NDR89_00750) 179569..180621 - 1053 WP_252251946.1 MFS transporter -
NDR89_RS00755 (NDR89_00755) 180882..181277 + 396 WP_053823866.1 lysozyme inhibitor LprI family protein -
NDR89_RS00760 (NDR89_00760) 181293..183704 - 2412 WP_252251947.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(7-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11285.06 Da        Isoelectric Point: 10.7461

>T247938 WP_174780282.1 NZ_CP098735:c179193-178888 [Cupriavidus gilardii]
MIEIREYPPFRRWLSGLPDEATKAVIARRLMRLSVGNFGDAKSVGGGVSELRIDYGPGFRVYFAREGPRVVLLLGGGDKS
TQHLDIRKAQALWAEIKRTQA

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10773.23 Da        Isoelectric Point: 4.6290

>AT247938 WP_082371731.1 NZ_CP098735:c178891-178589 [Cupriavidus gilardii]
MKDLEYRTFDPARYLDTDEARAAFLADALMDADHPELFAEALAAVARSRGNIAETAQAAGLSTSGLYKILGADSDPKLST
LRALLDVLGVELTIRPKLAH

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References