Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3006425..3007094 Replicon chromosome
Accession NZ_CP098724
Organism Yersinia ruckeri strain NVI-10571

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND438_RS13740 Protein ID WP_038241020.1
Coordinates 3006425..3006847 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND438_RS13745 Protein ID WP_004719196.1
Coordinates 3006828..3007094 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND438_RS13720 (ND438_13715) 3002264..3003997 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
ND438_RS13725 (ND438_13720) 3004004..3004720 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND438_RS13730 (ND438_13725) 3004752..3005651 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND438_RS13735 (ND438_13730) 3005759..3006277 + 519 WP_038241022.1 flavodoxin FldB -
ND438_RS13740 (ND438_13735) 3006425..3006847 - 423 WP_038241020.1 protein YgfX Toxin
ND438_RS13745 (ND438_13740) 3006828..3007094 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND438_RS13750 (ND438_13745) 3007388..3008380 + 993 WP_096823598.1 tRNA-modifying protein YgfZ -
ND438_RS13755 (ND438_13750) 3008519..3009184 - 666 WP_175537887.1 hemolysin III family protein -
ND438_RS13760 (ND438_13755) 3009501..3009757 + 257 Protein_2669 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247921 WP_038241020.1 NZ_CP098724:c3006847-3006425 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247921 WP_004719196.1 NZ_CP098724:c3007094-3006828 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References