Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 701754..702423 Replicon chromosome
Accession NZ_CP098723
Organism Yersinia ruckeri strain NVI-11065

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag ND444_RS03100 Protein ID WP_265315993.1
Coordinates 702001..702423 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND444_RS03095 Protein ID WP_004719196.1
Coordinates 701754..702020 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND444_RS03080 (ND444_03075) 699091..699347 - 257 Protein_594 HD domain-containing protein -
ND444_RS03085 (ND444_03080) 699664..700329 + 666 WP_175537887.1 hemolysin III family protein -
ND444_RS03090 (ND444_03085) 700468..701460 - 993 WP_038241018.1 tRNA-modifying protein YgfZ -
ND444_RS03095 (ND444_03090) 701754..702020 + 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND444_RS03100 (ND444_03095) 702001..702423 + 423 WP_265315993.1 protein YgfX Toxin
ND444_RS03105 (ND444_03100) 702571..703089 - 519 WP_038241022.1 flavodoxin FldB -
ND444_RS03110 (ND444_03105) 703197..704096 + 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND444_RS03115 (ND444_03110) 704128..704844 + 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND444_RS03120 (ND444_03115) 704851..706584 + 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16511.51 Da        Isoelectric Point: 11.1478

>T247902 WP_265315993.1 NZ_CP098723:702001-702423 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDFAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247902 WP_004719196.1 NZ_CP098723:701754-702020 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References