Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2820782..2821451 Replicon chromosome
Accession NZ_CP098722
Organism Yersinia ruckeri strain NVI-11073

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND439_RS12720 Protein ID WP_038241020.1
Coordinates 2820782..2821204 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND439_RS12725 Protein ID WP_004719196.1
Coordinates 2821185..2821451 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND439_RS12700 (ND439_12690) 2816621..2818354 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
ND439_RS12705 (ND439_12695) 2818361..2819077 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND439_RS12710 (ND439_12700) 2819109..2820008 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND439_RS12715 (ND439_12705) 2820116..2820634 + 519 WP_038241022.1 flavodoxin FldB -
ND439_RS12720 (ND439_12710) 2820782..2821204 - 423 WP_038241020.1 protein YgfX Toxin
ND439_RS12725 (ND439_12715) 2821185..2821451 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND439_RS12730 (ND439_12720) 2821745..2822737 + 993 WP_038241018.1 tRNA-modifying protein YgfZ -
ND439_RS12735 (ND439_12725) 2822876..2823541 - 666 WP_175537887.1 hemolysin III family protein -
ND439_RS12740 (ND439_12730) 2823858..2824114 + 257 Protein_2468 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247901 WP_038241020.1 NZ_CP098722:c2821204-2820782 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247901 WP_004719196.1 NZ_CP098722:c2821451-2821185 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References