Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3202416..3203085 Replicon chromosome
Accession NZ_CP098719
Organism Yersinia ruckeri strain NVI-11267

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND445_RS14795 Protein ID WP_038241020.1
Coordinates 3202416..3202838 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND445_RS14800 Protein ID WP_004719196.1
Coordinates 3202819..3203085 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND445_RS14775 (ND445_14770) 3198255..3199988 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
ND445_RS14780 (ND445_14775) 3199995..3200711 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND445_RS14785 (ND445_14780) 3200743..3201642 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND445_RS14790 (ND445_14785) 3201750..3202268 + 519 WP_038241022.1 flavodoxin FldB -
ND445_RS14795 (ND445_14790) 3202416..3202838 - 423 WP_038241020.1 protein YgfX Toxin
ND445_RS14800 (ND445_14795) 3202819..3203085 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND445_RS14805 (ND445_14800) 3203379..3204371 + 993 WP_096823598.1 tRNA-modifying protein YgfZ -
ND445_RS14810 (ND445_14805) 3204510..3205175 - 666 WP_175537887.1 hemolysin III family protein -
ND445_RS14815 (ND445_14810) 3205492..3205748 + 257 Protein_2872 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247893 WP_038241020.1 NZ_CP098719:c3202838-3202416 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247893 WP_004719196.1 NZ_CP098719:c3203085-3202819 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References