247885

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 609632..611352 Replicon chromosome
Accession NZ_CP098719
Organism Yersinia ruckeri strain NVI-11267

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ND445_RS02780 Protein ID WP_096823271.1
Coordinates 609632..610288 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag ND445_RS02785 Protein ID WP_096823272.1
Coordinates 610285..611352 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND445_RS02750 (ND445_02750) 604851..605795 - 945 WP_038275265.1 hypothetical protein -
ND445_RS02755 (ND445_02755) 606310..607569 + 1260 Protein_532 integrase arm-type DNA-binding domain-containing protein -
ND445_RS02760 (ND445_02760) 607743..607997 + 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
ND445_RS02765 (ND445_02765) 607987..608277 + 291 WP_071666901.1 type II toxin-antitoxin system RelE/ParE family toxin -
ND445_RS02770 (ND445_02770) 608541..608930 + 390 WP_096823270.1 restriction endonuclease subunit S -
ND445_RS02775 (ND445_02775) 609054..609629 + 576 WP_071706520.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
ND445_RS02780 (ND445_02780) 609632..610288 + 657 WP_096823271.1 DUF4433 domain-containing protein Toxin
ND445_RS02785 (ND445_02785) 610285..611352 + 1068 WP_096823272.1 macro domain-containing protein Antitoxin
ND445_RS02790 (ND445_02790) 611373..611639 + 267 Protein_539 hypothetical protein -
ND445_RS02795 (ND445_02795) 611714..611848 + 135 Protein_540 transposase -
ND445_RS02800 (ND445_02800) 611851..612348 + 498 Protein_541 IS30-like element ISYkr1 family transposase -
ND445_RS02805 (ND445_02805) 612354..613047 + 694 Protein_542 IS3 family transposase -
ND445_RS02810 (ND445_02810) 613357..614268 - 912 WP_096823274.1 EamA family transporter -
ND445_RS02815 (ND445_02815) 614425..615102 + 678 WP_096823275.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 598180..616437 18257


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25214.72 Da        Isoelectric Point: 6.6007

>T247885 WP_096823271.1 NZ_CP098719:609632-610288 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLANYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40847.21 Da        Isoelectric Point: 6.3136

>AT247885 WP_096823272.1 NZ_CP098719:610285-611352 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References