Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 607743..608277 Replicon chromosome
Accession NZ_CP098719
Organism Yersinia ruckeri strain NVI-11267

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ND445_RS02765 Protein ID WP_071666901.1
Coordinates 607987..608277 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A1JJ37
Locus tag ND445_RS02760 Protein ID WP_005175264.1
Coordinates 607743..607997 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND445_RS02750 (ND445_02750) 604851..605795 - 945 WP_038275265.1 hypothetical protein -
ND445_RS02755 (ND445_02755) 606310..607569 + 1260 Protein_532 integrase arm-type DNA-binding domain-containing protein -
ND445_RS02760 (ND445_02760) 607743..607997 + 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ND445_RS02765 (ND445_02765) 607987..608277 + 291 WP_071666901.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ND445_RS02770 (ND445_02770) 608541..608930 + 390 WP_096823270.1 restriction endonuclease subunit S -
ND445_RS02775 (ND445_02775) 609054..609629 + 576 WP_071706520.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
ND445_RS02780 (ND445_02780) 609632..610288 + 657 WP_096823271.1 DUF4433 domain-containing protein -
ND445_RS02785 (ND445_02785) 610285..611352 + 1068 WP_096823272.1 macro domain-containing protein -
ND445_RS02790 (ND445_02790) 611373..611639 + 267 Protein_539 hypothetical protein -
ND445_RS02795 (ND445_02795) 611714..611848 + 135 Protein_540 transposase -
ND445_RS02800 (ND445_02800) 611851..612348 + 498 Protein_541 IS30-like element ISYkr1 family transposase -
ND445_RS02805 (ND445_02805) 612354..613047 + 694 Protein_542 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 598180..616437 18257


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11421.37 Da        Isoelectric Point: 9.9816

>T247884 WP_071666901.1 NZ_CP098719:607987-608277 [Yersinia ruckeri]
MTFNIDFDERALKEWHKLDKTIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRASGFRLIYQVIDEEIVILIVAVG
KREDEKAYDLAKKRIQ

Download         Length: 291 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9680.07 Da        Isoelectric Point: 4.8283

>AT247884 WP_005175264.1 NZ_CP098719:607743-607997 [Yersinia ruckeri]
MSTIQIRVDDELKKSAYQAFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSNQDEDADILAVVRERLKNPAKRIRVN
IDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A1JJ37

References