Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3050478..3051147 Replicon chromosome
Accession NZ_CP098716
Organism Yersinia ruckeri strain NVI-11294

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND011_RS14120 Protein ID WP_038241020.1
Coordinates 3050478..3050900 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND011_RS14125 Protein ID WP_004719196.1
Coordinates 3050881..3051147 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND011_RS14100 (ND011_14090) 3046317..3048050 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
ND011_RS14105 (ND011_14095) 3048057..3048773 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND011_RS14110 (ND011_14100) 3048805..3049704 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND011_RS14115 (ND011_14105) 3049812..3050330 + 519 WP_038241022.1 flavodoxin FldB -
ND011_RS14120 (ND011_14110) 3050478..3050900 - 423 WP_038241020.1 protein YgfX Toxin
ND011_RS14125 (ND011_14115) 3050881..3051147 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND011_RS14130 (ND011_14120) 3051441..3052433 + 993 WP_096823598.1 tRNA-modifying protein YgfZ -
ND011_RS14135 (ND011_14125) 3052572..3053237 - 666 WP_175537887.1 hemolysin III family protein -
ND011_RS14140 (ND011_14130) 3053554..3053810 + 257 Protein_2741 HD domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247882 WP_038241020.1 NZ_CP098716:c3050900-3050478 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247882 WP_004719196.1 NZ_CP098716:c3051147-3050881 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A380QS17


Antitoxin

Source ID Structure

References