Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1921437..1922355 Replicon chromosome
Accession NZ_CP098716
Organism Yersinia ruckeri strain NVI-11294

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ND011_RS08745 Protein ID WP_038242633.1
Coordinates 1921897..1922355 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag ND011_RS08740 Protein ID WP_038242631.1
Coordinates 1921437..1921883 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND011_RS08720 (ND011_08710) 1917135..1917839 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
ND011_RS08725 (ND011_08715) 1917850..1918824 - 975 WP_071706618.1 L-Ala-D/L-Glu epimerase -
ND011_RS08730 (ND011_08720) 1918974..1919477 + 504 WP_004717547.1 thiol peroxidase -
ND011_RS08735 (ND011_08725) 1919512..1921119 - 1608 WP_096823414.1 transcriptional regulator TyrR -
ND011_RS08740 (ND011_08730) 1921437..1921883 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
ND011_RS08745 (ND011_08735) 1921897..1922355 + 459 WP_038242633.1 RES domain-containing protein Toxin
ND011_RS08750 (ND011_08740) 1922359..1923417 - 1059 WP_038242635.1 YcjF family protein -
ND011_RS08755 (ND011_08745) 1923414..1924811 - 1398 WP_004717556.1 YcjX family protein -
ND011_RS08760 (ND011_08750) 1924792..1925034 - 243 WP_096823415.1 phage shock protein PspD -
ND011_RS08765 (ND011_08755) 1925098..1925457 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
ND011_RS08770 (ND011_08760) 1925457..1925684 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
ND011_RS08775 (ND011_08765) 1925768..1926433 - 666 WP_038275968.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T247876 WP_038242633.1 NZ_CP098716:1921897-1922355 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT247876 WP_038242631.1 NZ_CP098716:1921437-1921883 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References