Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3069987..3070656 Replicon chromosome
Accession NZ_CP098714
Organism Yersinia ruckeri strain NVI-1176

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND442_RS14225 Protein ID WP_038241020.1
Coordinates 3069987..3070409 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND442_RS14230 Protein ID WP_004719196.1
Coordinates 3070390..3070656 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND442_RS14205 (ND442_14200) 3065826..3067559 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
ND442_RS14210 (ND442_14205) 3067566..3068282 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND442_RS14215 (ND442_14210) 3068314..3069213 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND442_RS14220 (ND442_14215) 3069321..3069839 + 519 WP_038241022.1 flavodoxin FldB -
ND442_RS14225 (ND442_14220) 3069987..3070409 - 423 WP_038241020.1 protein YgfX Toxin
ND442_RS14230 (ND442_14225) 3070390..3070656 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND442_RS14235 (ND442_14230) 3070950..3071942 + 993 WP_096823598.1 tRNA-modifying protein YgfZ -
ND442_RS14240 (ND442_14235) 3072081..3072746 - 666 WP_175537887.1 hemolysin III family protein -
ND442_RS14245 (ND442_14240) 3073063..3073319 + 257 Protein_2766 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247871 WP_038241020.1 NZ_CP098714:c3070409-3069987 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247871 WP_004719196.1 NZ_CP098714:c3070656-3070390 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References