Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 457650..459370 | Replicon | chromosome |
Accession | NZ_CP098714 | ||
Organism | Yersinia ruckeri strain NVI-1176 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | ND442_RS02100 | Protein ID | WP_096823271.1 |
Coordinates | 457650..458306 (+) | Length | 219 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | ND442_RS02105 | Protein ID | WP_096823272.1 |
Coordinates | 458303..459370 (+) | Length | 356 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ND442_RS02070 (ND442_02070) | 452869..453813 | - | 945 | WP_038275265.1 | hypothetical protein | - |
ND442_RS02075 (ND442_02075) | 454328..455587 | + | 1260 | Protein_400 | integrase arm-type DNA-binding domain-containing protein | - |
ND442_RS02080 (ND442_02080) | 455761..456015 | + | 255 | WP_005175264.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
ND442_RS02085 (ND442_02085) | 456005..456295 | + | 291 | WP_071666901.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
ND442_RS02090 (ND442_02090) | 456559..456948 | + | 390 | WP_096823270.1 | restriction endonuclease subunit S | - |
ND442_RS02095 (ND442_02095) | 457072..457647 | + | 576 | WP_071706520.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
ND442_RS02100 (ND442_02100) | 457650..458306 | + | 657 | WP_096823271.1 | DUF4433 domain-containing protein | Toxin |
ND442_RS02105 (ND442_02105) | 458303..459370 | + | 1068 | WP_096823272.1 | macro domain-containing protein | Antitoxin |
ND442_RS02110 (ND442_02110) | 459391..459657 | + | 267 | Protein_407 | hypothetical protein | - |
ND442_RS02115 (ND442_02115) | 459732..459866 | + | 135 | Protein_408 | transposase | - |
ND442_RS02120 (ND442_02120) | 459869..460366 | + | 498 | Protein_409 | IS30-like element ISYkr1 family transposase | - |
ND442_RS02125 (ND442_02125) | 460372..461065 | + | 694 | Protein_410 | IS3 family transposase | - |
ND442_RS02130 (ND442_02130) | 461375..462286 | - | 912 | WP_096823274.1 | EamA family transporter | - |
ND442_RS02135 (ND442_02135) | 462443..463120 | + | 678 | WP_096823275.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 446198..464455 | 18257 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 219 a.a. Molecular weight: 25214.72 Da Isoelectric Point: 6.6007
>T247863 WP_096823271.1 NZ_CP098714:457650-458306 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLANYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLANYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS
Download Length: 657 bp
Antitoxin
Download Length: 356 a.a. Molecular weight: 40847.21 Da Isoelectric Point: 6.3136
>AT247863 WP_096823272.1 NZ_CP098714:458303-459370 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC
Download Length: 1068 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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