Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 3038668..3039348 Replicon chromosome
Accession NZ_CP098710
Organism Yersinia ruckeri strain NVI-4479

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag ND012_RS13820 Protein ID WP_265320780.1
Coordinates 3038668..3038988 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A0T9UF43
Locus tag ND012_RS13825 Protein ID WP_050082065.1
Coordinates 3039025..3039348 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND012_RS13805 (ND012_13795) 3035461..3037302 + 1842 WP_004723328.1 RNA polymerase sigma factor RpoD -
ND012_RS13815 (ND012_13805) 3037722..3038555 - 834 WP_265320781.1 DUF4942 domain-containing protein -
ND012_RS13820 (ND012_13810) 3038668..3038988 - 321 WP_265320780.1 toxin Toxin
ND012_RS13825 (ND012_13815) 3039025..3039348 - 324 WP_050082065.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
ND012_RS13830 (ND012_13820) 3039361..3039831 - 471 WP_234054729.1 DNA repair protein RadC -
ND012_RS13835 (ND012_13825) 3039902..3040591 - 690 Protein_2683 DUF932 domain-containing protein -
ND012_RS13840 (ND012_13830) 3041173..3042873 + 1701 WP_049600104.1 group II intron reverse transcriptase/maturase -
ND012_RS13845 (ND012_13835) 3042955..3043086 - 132 Protein_2685 DUF945 domain-containing protein -
ND012_RS13850 (ND012_13840) 3043207..3043659 - 453 WP_234054727.1 IrmA family protein -
ND012_RS13855 (ND012_13845) 3043656..3044108 - 453 WP_234054726.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12042.65 Da        Isoelectric Point: 6.6413

>T247850 WP_265320780.1 NZ_CP098710:c3038988-3038668 [Yersinia ruckeri]
MHISSVPATVPVASRLSPVQVWQQLLTYLLDHHYGLTLNDTPFHNDAAIQEHIEAGITLSDAVNFLVERYELVRSDRKGF
SWQEQTPFLTTTDILRARRATGLINK

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11976.55 Da        Isoelectric Point: 5.9437

>AT247850 WP_050082065.1 NZ_CP098710:c3039348-3039025 [Yersinia ruckeri]
MPLTPPHEWGLQSDITPRFGARLVQEGNRLHYLADRAGLTGSFSPEQLQKLDQAFPLFIDQLEAMLHSGELNPHQQHQVT
IQLASLTCIADTRGSCGYVYISIYPTQ

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9UF43

References