Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2889104..2889773 Replicon chromosome
Accession NZ_CP098710
Organism Yersinia ruckeri strain NVI-4479

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND012_RS13155 Protein ID WP_038241020.1
Coordinates 2889104..2889526 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND012_RS13160 Protein ID WP_004719196.1
Coordinates 2889507..2889773 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND012_RS13135 (ND012_13125) 2884943..2886676 - 1734 WP_038241024.1 single-stranded-DNA-specific exonuclease RecJ -
ND012_RS13140 (ND012_13130) 2886683..2887399 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND012_RS13145 (ND012_13135) 2887431..2888330 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND012_RS13150 (ND012_13140) 2888438..2888956 + 519 WP_038241022.1 flavodoxin FldB -
ND012_RS13155 (ND012_13145) 2889104..2889526 - 423 WP_038241020.1 protein YgfX Toxin
ND012_RS13160 (ND012_13150) 2889507..2889773 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND012_RS13165 (ND012_13155) 2890067..2891059 + 993 WP_038241018.1 tRNA-modifying protein YgfZ -
ND012_RS13170 (ND012_13160) 2891198..2891863 - 666 WP_175537887.1 hemolysin III family protein -
ND012_RS13175 (ND012_13165) 2892180..2892436 + 257 Protein_2554 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247849 WP_038241020.1 NZ_CP098710:c2889526-2889104 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247849 WP_004719196.1 NZ_CP098710:c2889773-2889507 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References