247843

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 914802..915425 Replicon chromosome
Accession NZ_CP098710
Organism Yersinia ruckeri strain NVI-4479

Toxin (Protein)


Gene name Hha Uniprot ID A0A085U5C4
Locus tag ND012_RS04120 Protein ID WP_038243726.1
Coordinates 914802..915005 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A085U5C5
Locus tag ND012_RS04125 Protein ID WP_004718732.1
Coordinates 915057..915425 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND012_RS04095 (ND012_04090) 910657..910995 + 339 WP_007886947.1 P-II family nitrogen regulator -
ND012_RS04100 (ND012_04095) 911034..912323 + 1290 WP_265320500.1 ammonium transporter AmtB -
ND012_RS04105 (ND012_04100) 912438..913301 - 864 WP_004718726.1 acyl-CoA thioesterase II -
ND012_RS04110 (ND012_04105) 913679..913993 - 315 WP_248577445.1 MGMT family protein -
ND012_RS04120 (ND012_04115) 914802..915005 - 204 WP_038243726.1 expression modulating protein YmoA Toxin
ND012_RS04125 (ND012_04120) 915057..915425 - 369 WP_004718732.1 Hha toxicity modulator TomB Antitoxin
ND012_RS04130 (ND012_04125) 916474..916635 + 162 WP_004718735.1 hypothetical protein -
ND012_RS04135 (ND012_04130) 916754..916897 - 144 WP_004718738.1 type B 50S ribosomal protein L36 -
ND012_RS04140 (ND012_04135) 916917..917171 - 255 WP_038243728.1 type B 50S ribosomal protein L31 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-117)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8037.27 Da        Isoelectric Point: 6.4573

>T247843 WP_038243726.1 NZ_CP098710:c915005-914802 [Yersinia ruckeri]
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPATVWQHVK

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14277.08 Da        Isoelectric Point: 4.4225

>AT247843 WP_004718732.1 NZ_CP098710:c915425-915057 [Yersinia ruckeri]
MDEYSPKRHDIAQLKFLCENLYDEGIATLGDSHHGWVNDPTSAVNLQLNDLIEHIASFVMSFKIKYADEIDLCELVEEYL
DDTYTLFSSYGINDPDLRRWQKTKDRLFRLFSGEYLCALMKN

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A085U5C4

Antitoxin

Source ID Structure
AlphaFold DB A0A085U5C5

References