247823

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1661812..1662730 Replicon chromosome
Accession NZ_CP098703
Organism Yersinia ruckeri strain NVI-4840

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ND437_RS07740 Protein ID WP_038242633.1
Coordinates 1661812..1662270 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag ND437_RS07745 Protein ID WP_038242631.1
Coordinates 1662284..1662730 (-) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND437_RS07710 (ND437_07710) 1657734..1658399 + 666 WP_038275968.1 phage shock protein PspA -
ND437_RS07715 (ND437_07715) 1658483..1658710 + 228 WP_038242637.1 envelope stress response membrane protein PspB -
ND437_RS07720 (ND437_07720) 1658710..1659069 + 360 WP_004717559.1 envelope stress response membrane protein PspC -
ND437_RS07725 (ND437_07725) 1659133..1659375 + 243 WP_087931058.1 phage shock protein PspD -
ND437_RS07730 (ND437_07730) 1659356..1660753 + 1398 WP_004717556.1 YcjX family protein -
ND437_RS07735 (ND437_07735) 1660750..1661808 + 1059 WP_038242635.1 YcjF family protein -
ND437_RS07740 (ND437_07740) 1661812..1662270 - 459 WP_038242633.1 RES domain-containing protein Toxin
ND437_RS07745 (ND437_07745) 1662284..1662730 - 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
ND437_RS07750 (ND437_07750) 1663048..1664655 + 1608 WP_038242630.1 transcriptional regulator TyrR -
ND437_RS07755 (ND437_07755) 1664690..1665193 - 504 WP_004717547.1 thiol peroxidase -
ND437_RS07760 (ND437_07760) 1665343..1666317 + 975 WP_248578615.1 L-Ala-D/L-Glu epimerase -
ND437_RS07765 (ND437_07765) 1666328..1667032 - 705 WP_004717543.1 murein tripeptide amidase MpaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T247823 WP_038242633.1 NZ_CP098703:c1662270-1661812 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT247823 WP_038242631.1 NZ_CP098703:c1662730-1662284 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References