Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 648223..648892 Replicon chromosome
Accession NZ_CP098703
Organism Yersinia ruckeri strain NVI-4840

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND437_RS02825 Protein ID WP_038241020.1
Coordinates 648470..648892 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND437_RS02820 Protein ID WP_004719196.1
Coordinates 648223..648489 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND437_RS02805 (ND437_02800) 645560..645816 - 257 Protein_547 HD domain-containing protein -
ND437_RS02810 (ND437_02805) 646133..646798 + 666 WP_175537887.1 hemolysin III family protein -
ND437_RS02815 (ND437_02810) 646937..647929 - 993 WP_038241018.1 tRNA-modifying protein YgfZ -
ND437_RS02820 (ND437_02815) 648223..648489 + 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND437_RS02825 (ND437_02820) 648470..648892 + 423 WP_038241020.1 protein YgfX Toxin
ND437_RS02830 (ND437_02825) 649040..649558 - 519 WP_038241022.1 flavodoxin FldB -
ND437_RS02835 (ND437_02830) 649666..650565 + 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND437_RS02840 (ND437_02835) 650597..651313 + 717 WP_038276201.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND437_RS02845 (ND437_02840) 651320..653053 + 1734 WP_267263262.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247818 WP_038241020.1 NZ_CP098703:648470-648892 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247818 WP_004719196.1 NZ_CP098703:648223-648489 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References