247809

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1896756..1897674 Replicon chromosome
Accession NZ_CP098701
Organism Yersinia ruckeri strain NVI-5089

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ND440_RS08515 Protein ID WP_265318566.1
Coordinates 1897216..1897674 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag ND440_RS08510 Protein ID WP_038242631.1
Coordinates 1896756..1897202 (+) Length 149 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND440_RS08490 (ND440_08485) 1892454..1893158 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
ND440_RS08495 (ND440_08490) 1893169..1894143 - 975 WP_071666721.1 L-Ala-D/L-Glu epimerase -
ND440_RS08500 (ND440_08495) 1894293..1894796 + 504 WP_004717547.1 thiol peroxidase -
ND440_RS08505 (ND440_08500) 1894831..1896438 - 1608 WP_038251390.1 transcriptional regulator TyrR -
ND440_RS08510 (ND440_08505) 1896756..1897202 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
ND440_RS08515 (ND440_08510) 1897216..1897674 + 459 WP_265318566.1 RES domain-containing protein Toxin
ND440_RS08520 (ND440_08515) 1897678..1898736 - 1059 WP_248578616.1 YcjF family protein -
ND440_RS08525 (ND440_08520) 1898733..1900130 - 1398 WP_004717556.1 YcjX family protein -
ND440_RS08530 (ND440_08525) 1900111..1900353 - 243 WP_087931058.1 phage shock protein PspD -
ND440_RS08535 (ND440_08530) 1900417..1900776 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
ND440_RS08540 (ND440_08535) 1900776..1901003 - 228 WP_248578617.1 envelope stress response membrane protein PspB -
ND440_RS08545 (ND440_08540) 1901087..1901752 - 666 WP_004717561.1 phage shock protein PspA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-147)

Antitoxin

(94-145)


Sequences


Toxin        


Download         Length: 153 a.a.        Molecular weight: 17019.50 Da        Isoelectric Point: 6.3201

>T247809 WP_265318566.1 NZ_CP098701:1897216-1897674 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPCLK

Download         Length: 459 bp


Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT247809 WP_038242631.1 NZ_CP098701:1896756-1897202 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References