Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 698318..698987 Replicon chromosome
Accession NZ_CP098701
Organism Yersinia ruckeri strain NVI-5089

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND440_RS03055 Protein ID WP_038241020.1
Coordinates 698565..698987 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND440_RS03050 Protein ID WP_004719196.1
Coordinates 698318..698584 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND440_RS03035 (ND440_03035) 695655..695911 - 257 Protein_586 HD domain-containing protein -
ND440_RS03040 (ND440_03040) 696228..696893 + 666 WP_175537887.1 hemolysin III family protein -
ND440_RS03045 (ND440_03045) 697032..698024 - 993 WP_038241018.1 tRNA-modifying protein YgfZ -
ND440_RS03050 (ND440_03050) 698318..698584 + 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND440_RS03055 (ND440_03055) 698565..698987 + 423 WP_038241020.1 protein YgfX Toxin
ND440_RS03060 (ND440_03060) 699135..699653 - 519 WP_038241022.1 flavodoxin FldB -
ND440_RS03065 (ND440_03065) 699761..700660 + 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND440_RS03070 (ND440_03070) 700692..701408 + 717 WP_038276201.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND440_RS03075 (ND440_03075) 701415..703148 + 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247807 WP_038241020.1 NZ_CP098701:698565-698987 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247807 WP_004719196.1 NZ_CP098701:698318-698584 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References