Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2998619..2999288 Replicon chromosome
Accession NZ_CP098695
Organism Yersinia ruckeri strain NVI-701

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND443_RS13730 Protein ID WP_038241020.1
Coordinates 2998619..2999041 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND443_RS13735 Protein ID WP_004719196.1
Coordinates 2999022..2999288 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND443_RS13710 (ND443_13695) 2994458..2996191 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
ND443_RS13715 (ND443_13700) 2996198..2996914 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND443_RS13720 (ND443_13705) 2996946..2997845 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND443_RS13725 (ND443_13710) 2997953..2998471 + 519 WP_038241022.1 flavodoxin FldB -
ND443_RS13730 (ND443_13715) 2998619..2999041 - 423 WP_038241020.1 protein YgfX Toxin
ND443_RS13735 (ND443_13720) 2999022..2999288 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND443_RS13740 (ND443_13725) 2999582..3000574 + 993 WP_096823598.1 tRNA-modifying protein YgfZ -
ND443_RS13745 (ND443_13730) 3000713..3001378 - 666 WP_175537887.1 hemolysin III family protein -
ND443_RS13750 (ND443_13735) 3001695..3001951 + 257 Protein_2667 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247792 WP_038241020.1 NZ_CP098695:c2999041-2998619 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247792 WP_004719196.1 NZ_CP098695:c2999288-2999022 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References