Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 457656..459376 Replicon chromosome
Accession NZ_CP098695
Organism Yersinia ruckeri strain NVI-701

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ND443_RS02095 Protein ID WP_096823271.1
Coordinates 457656..458312 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag ND443_RS02100 Protein ID WP_096823272.1
Coordinates 458309..459376 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND443_RS02065 (ND443_02065) 452875..453819 - 945 WP_038275265.1 hypothetical protein -
ND443_RS02070 (ND443_02070) 454334..455593 + 1260 Protein_399 integrase arm-type DNA-binding domain-containing protein -
ND443_RS02075 (ND443_02075) 455767..456021 + 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
ND443_RS02080 (ND443_02080) 456011..456301 + 291 WP_071666901.1 type II toxin-antitoxin system RelE/ParE family toxin -
ND443_RS02085 (ND443_02085) 456565..456954 + 390 WP_096823270.1 restriction endonuclease subunit S -
ND443_RS02090 (ND443_02090) 457078..457653 + 576 WP_071706520.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
ND443_RS02095 (ND443_02095) 457656..458312 + 657 WP_096823271.1 DUF4433 domain-containing protein Toxin
ND443_RS02100 (ND443_02100) 458309..459376 + 1068 WP_096823272.1 macro domain-containing protein Antitoxin
ND443_RS02105 (ND443_02105) 459397..459663 + 267 Protein_406 hypothetical protein -
ND443_RS02110 (ND443_02110) 459738..459872 + 135 Protein_407 transposase -
ND443_RS02115 (ND443_02115) 459875..460372 + 498 Protein_408 IS30-like element ISYkr1 family transposase -
ND443_RS02120 (ND443_02120) 460378..461071 + 694 Protein_409 IS3 family transposase -
ND443_RS02125 (ND443_02125) 461381..462292 - 912 WP_096823274.1 EamA family transporter -
ND443_RS02130 (ND443_02130) 462449..463126 + 678 WP_096823275.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 446204..464461 18257


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25214.72 Da        Isoelectric Point: 6.6007

>T247784 WP_096823271.1 NZ_CP098695:457656-458312 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLANYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40847.21 Da        Isoelectric Point: 6.3136

>AT247784 WP_096823272.1 NZ_CP098695:458309-459376 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References