Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1703364..1704282 Replicon chromosome
Accession NZ_CP098694
Organism Yersinia ruckeri strain NVI-8270

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ND446_RS07835 Protein ID WP_234056461.1
Coordinates 1703364..1703822 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag ND446_RS07840 Protein ID WP_038242631.1
Coordinates 1703836..1704282 (-) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND446_RS07805 (ND446_07805) 1699286..1699951 + 666 WP_145497062.1 phage shock protein PspA -
ND446_RS07810 (ND446_07810) 1700035..1700262 + 228 WP_038242637.1 envelope stress response membrane protein PspB -
ND446_RS07815 (ND446_07815) 1700262..1700621 + 360 WP_004717559.1 envelope stress response membrane protein PspC -
ND446_RS07820 (ND446_07820) 1700784..1700927 + 144 WP_234049335.1 phage shock protein PspD -
ND446_RS07825 (ND446_07825) 1700908..1702305 + 1398 WP_004717556.1 YcjX family protein -
ND446_RS07830 (ND446_07830) 1702302..1703360 + 1059 WP_038242635.1 YcjF family protein -
ND446_RS07835 (ND446_07835) 1703364..1703822 - 459 WP_234056461.1 RES domain-containing protein Toxin
ND446_RS07840 (ND446_07840) 1703836..1704282 - 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
ND446_RS07845 (ND446_07845) 1704600..1706207 + 1608 WP_038251390.1 transcriptional regulator TyrR -
ND446_RS07850 (ND446_07850) 1706242..1706745 - 504 WP_004717547.1 thiol peroxidase -
ND446_RS07855 (ND446_07855) 1706895..1707869 + 975 WP_234056460.1 L-Ala-D/L-Glu epimerase -
ND446_RS07860 (ND446_07860) 1707880..1708584 - 705 WP_004717543.1 murein tripeptide amidase MpaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17067.54 Da        Isoelectric Point: 6.7537

>T247778 WP_234056461.1 NZ_CP098694:c1703822-1703364 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSASSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSIHPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT247778 WP_038242631.1 NZ_CP098694:c1704282-1703836 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References