Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 740478..741147 Replicon chromosome
Accession NZ_CP098694
Organism Yersinia ruckeri strain NVI-8270

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag ND446_RS03365 Protein ID WP_038241020.1
Coordinates 740725..741147 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ND446_RS03360 Protein ID WP_004719196.1
Coordinates 740478..740744 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ND446_RS03345 (ND446_03345) 737815..738071 - 257 Protein_647 HD domain-containing protein -
ND446_RS03350 (ND446_03350) 738388..739053 + 666 WP_175537887.1 hemolysin III family protein -
ND446_RS03355 (ND446_03355) 739192..740184 - 993 WP_038241018.1 tRNA-modifying protein YgfZ -
ND446_RS03360 (ND446_03360) 740478..740744 + 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
ND446_RS03365 (ND446_03365) 740725..741147 + 423 WP_038241020.1 protein YgfX Toxin
ND446_RS03370 (ND446_03370) 741295..741813 - 519 WP_038241022.1 flavodoxin FldB -
ND446_RS03375 (ND446_03375) 741921..742820 + 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
ND446_RS03380 (ND446_03380) 742852..743568 + 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ND446_RS03385 (ND446_03385) 743575..745308 + 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T247773 WP_038241020.1 NZ_CP098694:740725-741147 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT247773 WP_004719196.1 NZ_CP098694:740478-740744 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References