247755

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1094821..1095323 Replicon chromosome
Accession NZ_CP098611
Organism Phormidium yuhuli AB48

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NEA10_RS04695 Protein ID WP_252664105.1
Coordinates 1094821..1095075 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NEA10_RS04700 Protein ID WP_252664106.1
Coordinates 1095072..1095323 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NEA10_RS04670 (NEA10_04670) 1090158..1091177 + 1020 WP_252664100.1 long-chain acyl-[acyl-carrier-protein] reductase -
NEA10_RS04675 (NEA10_04675) 1091256..1092206 + 951 WP_252664101.1 acetyl-CoA carboxylase carboxyl transferase subunit alpha -
NEA10_RS04680 (NEA10_04680) 1092348..1092566 + 219 WP_252664102.1 hypothetical protein -
NEA10_RS04685 (NEA10_04685) 1092616..1093149 + 534 WP_252664103.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
NEA10_RS04690 (NEA10_04690) 1093146..1094780 - 1635 WP_252664104.1 hypothetical protein -
NEA10_RS04695 (NEA10_04695) 1094821..1095075 - 255 WP_252664105.1 Txe/YoeB family addiction module toxin Toxin
NEA10_RS04700 (NEA10_04700) 1095072..1095323 - 252 WP_252664106.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NEA10_RS04705 (NEA10_04705) 1095445..1096023 - 579 WP_252664107.1 Uma2 family endonuclease -
NEA10_RS04710 (NEA10_04710) 1096049..1098718 - 2670 WP_252664108.1 signal peptidase I -
NEA10_RS04715 (NEA10_04715) 1098905..1099252 + 348 WP_252664109.1 type II toxin-antitoxin system VapB family antitoxin -
NEA10_RS04720 (NEA10_04720) 1099310..1099795 + 486 WP_252664110.1 shikimate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10259.91 Da        Isoelectric Point: 10.0404

>T247755 WP_252664105.1 NZ_CP098611:c1095075-1094821 [Phormidium yuhuli AB48]
MKTTFSESAWDDYLYWQKMDKKILRRVNQLIKEIHRTPFEGIGKPEPLKHNLAGYWSRRITAEQRMVYKVTPDELMIAQL
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9296.55 Da        Isoelectric Point: 4.5959

>AT247755 WP_252664106.1 NZ_CP098611:c1095323-1095072 [Phormidium yuhuli AB48]
MDALSYTAARRNLAKTMQQVCEDHSPVIITRNKAASVVMMSLEDYEALQETAYLLRSPANARRLLESIAELEQGGGQERE
LLE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References