247753

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 939912..940489 Replicon chromosome
Accession NZ_CP098611
Organism Phormidium yuhuli AB48

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NEA10_RS04015 Protein ID WP_252663931.1
Coordinates 939912..940172 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NEA10_RS04020 Protein ID WP_252663932.1
Coordinates 940160..940489 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NEA10_RS03990 (NEA10_03990) 935277..935969 - 693 WP_252663925.1 Uma2 family endonuclease -
NEA10_RS03995 (NEA10_03995) 936057..936311 + 255 WP_252663926.1 NAD(P)H-quinone oxidoreductase subunit N -
NEA10_RS04000 (NEA10_04000) 936315..937091 - 777 WP_252663928.1 Uma2 family endonuclease -
NEA10_RS04005 (NEA10_04005) 937235..937912 + 678 WP_252663929.1 Uma2 family endonuclease -
NEA10_RS04010 (NEA10_04010) 938131..939801 + 1671 WP_252663930.1 NACHT domain-containing protein -
NEA10_RS04015 (NEA10_04015) 939912..940172 + 261 WP_252663931.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
NEA10_RS04020 (NEA10_04020) 940160..940489 + 330 WP_252663932.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
NEA10_RS04025 (NEA10_04025) 940579..943119 + 2541 WP_252663933.1 PBS lyase -
NEA10_RS04030 (NEA10_04030) 943502..943891 + 390 WP_252663934.1 hypothetical protein -
NEA10_RS04035 (NEA10_04035) 944134..945159 + 1026 WP_252663935.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

SpoVT-AbrB domain

(10-51)

Antitoxin

mRNA interferase PemK-like

(6-107)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9920.17 Da        Isoelectric Point: 4.6286

>T247753 WP_252663931.1 NZ_CP098611:939912-940172 [Phormidium yuhuli AB48]
MSKVIRTRIVKIGNSQGVRIPKLLLEQSGIQADVEIEVEGDHLTIRTARRLRNGWDQAFAAMAKEQDDVLLDQVNSTDWE
QSEWEW

Download         Length: 261 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12128.17 Da        Isoelectric Point: 7.8292

>AT247753 WP_252663932.1 NZ_CP098611:940160-940489 [Phormidium yuhuli AB48]
MGVVAQRFDVFLVNLDPTIGSEIQKTRPCVIISPDEMNRHIATVIIAPMTTKGKAYPTRIPCQFQGKEGKIVLDQIRTID
KTRLVKKLGQISPDEQSGVLDTLAEMFSE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References