247752

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 194271..195157 Replicon chromosome
Accession NZ_CP098611
Organism Phormidium yuhuli AB48

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag NEA10_RS00730 Protein ID WP_252663328.1
Coordinates 194271..194726 (-) Length 152 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag NEA10_RS00735 Protein ID WP_252663329.1
Coordinates 194723..195157 (-) Length 145 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NEA10_RS00715 (NEA10_00715) 189769..192486 - 2718 WP_252663325.1 CRISPR-associated protein Csc3 -
NEA10_RS00720 (NEA10_00720) 192613..193521 + 909 WP_252663326.1 WYL domain-containing protein -
NEA10_RS00725 (NEA10_00725) 193494..193727 - 234 WP_252663327.1 hypothetical protein -
NEA10_RS00730 (NEA10_00730) 194271..194726 - 456 WP_252663328.1 DUF86 domain-containing protein Toxin
NEA10_RS00735 (NEA10_00735) 194723..195157 - 435 WP_252663329.1 nucleotidyltransferase domain-containing protein Antitoxin
NEA10_RS00740 (NEA10_00740) 195406..196116 - 711 WP_252663330.1 hypothetical protein -
NEA10_RS00745 (NEA10_00745) 196170..198233 - 2064 WP_252663331.1 cation:proton antiporter -
NEA10_RS00750 (NEA10_00750) 198582..198830 - 249 WP_068790032.1 hypothetical protein -
NEA10_RS00755 (NEA10_00755) 198868..199629 - 762 WP_252663332.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(17-129)

Antitoxin

Polymerase beta, nucleotidyltransferase

(12-106)


Sequences

Toxin        


Download         Length: 152 a.a.        Molecular weight: 17492.07 Da        Isoelectric Point: 5.1959

>T247752 WP_252663328.1 NZ_CP098611:c194726-194271 [Phormidium yuhuli AB48]
MSQFDASVVWRRLQKINSFVARLKKFETITLADYLESEDNQLIAERLIQLCTEAALDINKYILSQLGVLDNKTHWTNKDY
FLEASRQNILTPDVARELADAASMRNILVHLYLDINPEIVFNSIQKSIMYYPLYVSQIAKYLDSLINTAQN

Download         Length: 456 bp

Antitoxin


Download         Length: 145 a.a.        Molecular weight: 16836.13 Da        Isoelectric Point: 4.7318

>AT247752 WP_252663329.1 NZ_CP098611:c195157-194723 [Phormidium yuhuli AB48]
MSNFLGLQVDLERLLHEIPYLKMLILFGSRARGDTHSNSDWDFAVLYNEELRRQTVEGFGWFRDIGIIGDCLNLNSDKID
VVEIERCSELMAHHIARDGKLIYEQEPGLFEDFKKENILSQKTIDDIIRESRSQVYQFLQKQGL

Download         Length: 435 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References