Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3871461..3872239 Replicon chromosome
Accession NZ_CP098604
Organism Xanthomonas hortorum pv. pelargonii strain OSU493

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NDY25_RS16710 Protein ID WP_168958945.1
Coordinates 3871461..3871952 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NDY25_RS16715 Protein ID WP_168958946.1
Coordinates 3871949..3872239 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDY25_RS16695 (NDY25_16670) 3868044..3868964 + 921 WP_168958943.1 30S ribosomal protein S6--L-glutamate ligase -
NDY25_RS16700 (NDY25_16675) 3869308..3869985 + 678 WP_006448355.1 response regulator transcription factor -
NDY25_RS16705 (NDY25_16680) 3869978..3871312 + 1335 WP_168958944.1 HAMP domain-containing sensor histidine kinase -
NDY25_RS16710 (NDY25_16685) 3871461..3871952 - 492 WP_168958945.1 GNAT family N-acetyltransferase Toxin
NDY25_RS16715 (NDY25_16690) 3871949..3872239 - 291 WP_168958946.1 DUF1778 domain-containing protein Antitoxin
NDY25_RS16720 (NDY25_16695) 3872315..3872716 - 402 WP_168958947.1 SymE family type I addiction module toxin -
NDY25_RS16725 (NDY25_16700) 3873248..3873871 - 624 WP_168958948.1 dephospho-CoA kinase -
NDY25_RS16730 (NDY25_16705) 3873885..3874748 - 864 WP_016849610.1 A24 family peptidase -
NDY25_RS16735 (NDY25_16710) 3874755..3876014 - 1260 WP_168958949.1 type II secretion system F family protein -
NDY25_RS16740 (NDY25_16715) 3876365..3876790 + 426 WP_168958950.1 pilin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3792278..3942189 149911


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17592.27 Da        Isoelectric Point: 9.6230

>T247747 WP_168958945.1 NZ_CP098604:c3871952-3871461 [Xanthomonas hortorum pv. pelargonii]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACADDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALVRDAGKRVLHAADTIGIRGLLVHALSTDAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10616.14 Da        Isoelectric Point: 10.5480

>AT247747 WP_168958946.1 NZ_CP098604:c3872239-3871949 [Xanthomonas hortorum pv. pelargonii]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFVLDAARSAAEEALLDQTLIAASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References