247745

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1976858..1977223 Replicon chromosome
Accession NZ_CP098604
Organism Xanthomonas hortorum pv. pelargonii strain OSU493

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag NDY25_RS08810 Protein ID WP_006451341.1
Coordinates 1976858..1976992 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag NDY25_RS08815 Protein ID WP_006451340.1
Coordinates 1977071..1977223 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDY25_RS08795 (NDY25_08780) 1973799..1974785 - 987 WP_233366624.1 MBL fold metallo-hydrolase -
NDY25_RS08800 (NDY25_08785) 1974944..1976233 - 1290 WP_168959806.1 tryptophan--tRNA ligase -
NDY25_RS08805 (NDY25_08790) 1976407..1976616 - 210 WP_251754913.1 CsbD family protein -
NDY25_RS08810 (NDY25_08795) 1976858..1976992 - 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
NDY25_RS08815 (NDY25_08800) 1977071..1977223 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
NDY25_RS08820 (NDY25_08805) 1977333..1978256 - 924 WP_046931980.1 arginase -
NDY25_RS08825 (NDY25_08810) 1978718..1979170 + 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
NDY25_RS08830 (NDY25_08815) 1979234..1979593 + 360 WP_006452081.1 hypothetical protein -
NDY25_RS08835 (NDY25_08820) 1979685..1980602 + 918 WP_168959807.1 hypothetical protein -
NDY25_RS08840 (NDY25_08825) 1980599..1981141 + 543 WP_006452083.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T247745 WP_006451341.1 NZ_CP098604:c1976992-1976858 [Xanthomonas hortorum pv. pelargonii]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT247745 WP_006451340.1 NZ_CP098604:c1977223-1977071 [Xanthomonas hortorum pv. pelargonii]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References