247744

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1572499..1573538 Replicon chromosome
Accession NZ_CP098604
Organism Xanthomonas hortorum pv. pelargonii strain OSU493

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag NDY25_RS06980 Protein ID WP_233366293.1
Coordinates 1572499..1573002 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag NDY25_RS06985 Protein ID WP_168957174.1
Coordinates 1573071..1573538 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDY25_RS06965 (NDY25_06950) 1568491..1571124 - 2634 WP_233366295.1 TonB-dependent receptor -
NDY25_RS06970 (NDY25_06955) 1571390..1571743 + 354 WP_043888904.1 6-carboxytetrahydropterin synthase QueD -
NDY25_RS06975 (NDY25_06960) 1571937..1572299 + 363 WP_006450461.1 phasin family protein -
NDY25_RS06980 (NDY25_06965) 1572499..1573002 - 504 WP_233366293.1 PIN domain-containing protein Toxin
NDY25_RS06985 (NDY25_06970) 1573071..1573538 - 468 WP_168957174.1 helix-turn-helix domain-containing protein Antitoxin
NDY25_RS06990 (NDY25_06975) 1573677..1574351 - 675 WP_168957175.1 dethiobiotin synthase -
NDY25_RS06995 (NDY25_06980) 1574470..1574952 + 483 WP_168957176.1 GAF domain-containing protein -
NDY25_RS07000 (NDY25_06985) 1574949..1575341 + 393 WP_168957177.1 TfoX/Sxy family protein -
NDY25_RS07005 (NDY25_06990) 1575454..1576404 - 951 WP_168957178.1 alpha/beta hydrolase-fold protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-91)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18783.57 Da        Isoelectric Point: 6.4861

>T247744 WP_233366293.1 NZ_CP098604:c1573002-1572499 [Xanthomonas hortorum pv. pelargonii]
MWLGLSGRFRARWSVQIHQEWKRNLLLNRRDLTAEQVDRTSALMDRAIPDALVTGHEPLIAGLQLPDADDRHVLAAAIRC
SASVIVTFNLKDFPSATLAPFGIEAQHPDEFIENLFDLDQAAVVSAAQRQRAQLTNPGMEVERYLEVLLRQGLVQTVKAL
TIYRTVL

Download         Length: 504 bp

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17375.85 Da        Isoelectric Point: 5.9974

>AT247744 WP_168957174.1 NZ_CP098604:c1573538-1573071 [Xanthomonas hortorum pv. pelargonii]
MSNIAPSKMVLPVEREVAAAVQGQRALAAYLATSFETQRIQIFDDQNQAHQVELPTSALRLLMDILAELADGNAVQVVPI
HAELTTQEAADLLNVSRPHMVKLMEEGALAFHRTGRHRRVRFADLMQFKRERERASEQAMQELATQAQELALGYQ

Download         Length: 468 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References