Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1089567..1090072 Replicon chromosome
Accession NZ_CP098604
Organism Xanthomonas hortorum pv. pelargonii strain OSU493

Toxin (Protein)


Gene name relE Uniprot ID V7ZHE2
Locus tag NDY25_RS04705 Protein ID WP_023902910.1
Coordinates 1089815..1090072 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6V7E8M0
Locus tag NDY25_RS04700 Protein ID WP_043888988.1
Coordinates 1089567..1089818 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDY25_RS04680 (NDY25_04665) 1084940..1086094 - 1155 WP_168959477.1 2-methylcitrate synthase -
NDY25_RS04685 (NDY25_04670) 1086170..1087018 - 849 WP_256627969.1 methylisocitrate lyase -
NDY25_RS04690 (NDY25_04675) 1087193..1088812 + 1620 WP_180336594.1 propionate catabolism operon regulatory protein PrpR -
NDY25_RS04695 (NDY25_04680) 1089055..1089381 - 327 WP_168959474.1 hypothetical protein -
NDY25_RS04700 (NDY25_04685) 1089567..1089818 + 252 WP_043888988.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NDY25_RS04705 (NDY25_04690) 1089815..1090072 + 258 WP_023902910.1 Txe/YoeB family addiction module toxin Toxin
NDY25_RS04715 (NDY25_04700) 1090579..1090932 - 354 WP_003483889.1 PilZ domain-containing protein -
NDY25_RS04720 (NDY25_04705) 1090929..1091888 - 960 WP_168959473.1 DNA polymerase III subunit delta' -
NDY25_RS04725 (NDY25_04710) 1091885..1092946 - 1062 WP_233366604.1 endolytic transglycosylase MltG -
NDY25_RS04730 (NDY25_04715) 1093019..1094374 - 1356 WP_168959472.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10170.68 Da        Isoelectric Point: 9.6587

>T247743 WP_023902910.1 NZ_CP098604:1089815-1090072 [Xanthomonas hortorum pv. pelargonii]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYA

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9269.50 Da        Isoelectric Point: 4.6536

>AT247743 WP_043888988.1 NZ_CP098604:1089567-1089818 [Xanthomonas hortorum pv. pelargonii]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7E8N0

Antitoxin

Source ID Structure
AlphaFold DB A0A6V7E8M0

References