Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | VapXD/- |
Location | 1411..1874 | Replicon | plasmid pJD1 |
Accession | NZ_CP098537 | ||
Organism | Neisseria gonorrhoeae strain 10771 |
Toxin (Protein)
Gene name | VapD | Uniprot ID | Q51003 |
Locus tag | NDQ63_RS11650 | Protein ID | WP_003690225.1 |
Coordinates | 1596..1874 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | VapX | Uniprot ID | Q51002 |
Locus tag | NDQ63_RS11645 | Protein ID | WP_003690223.1 |
Coordinates | 1411..1596 (+) | Length | 62 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NDQ63_RS11630 (NDQ63_11545) | 51..920 | + | 870 | WP_003690219.1 | replication initiation protein | - |
NDQ63_RS11635 (NDQ63_11550) | 924..1166 | + | 243 | WP_003690220.1 | HTH domain-containing protein | - |
NDQ63_RS11640 (NDQ63_11555) | 1163..1408 | + | 246 | WP_003690221.1 | hypothetical protein | - |
NDQ63_RS11645 (NDQ63_11560) | 1411..1596 | + | 186 | WP_003690223.1 | DUF5397 family protein | Antitoxin |
NDQ63_RS11650 (NDQ63_11565) | 1596..1874 | + | 279 | WP_003690225.1 | endoribonuclease VapD | Toxin |
NDQ63_RS11655 (NDQ63_11570) | 1852..2106 | - | 255 | WP_003690227.1 | Cryptic plasmid protein A | - |
NDQ63_RS11660 (NDQ63_11575) | 2153..2794 | - | 642 | WP_003690229.1 | MbeB family mobilization protein | - |
NDQ63_RS11665 (NDQ63_11580) | 2878..3507 | - | 630 | WP_003696452.1 | relaxase/mobilization nuclease domain-containing protein | - |
NDQ63_RS11670 (NDQ63_11585) | 3492..3872 | - | 381 | WP_014580441.1 | MobC family plasmid mobilization relaxosome protein | - |
NDQ63_RS11675 (NDQ63_11590) | 3951..4175 | + | 225 | WP_025455920.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..4207 | 4207 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7H5FJI5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q51002 |