Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2585965..2586497 Replicon chromosome
Accession NZ_CP098502
Organism Paraconexibacter antarcticus strain 02-257

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NBH00_RS12830 Protein ID WP_254568991.1
Coordinates 2586198..2586497 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NBH00_RS12825 Protein ID WP_254568990.1
Coordinates 2585965..2586198 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBH00_RS12790 (NBH00_12790) 2581258..2581593 + 336 WP_254568983.1 hypothetical protein -
NBH00_RS12795 (NBH00_12795) 2581567..2581815 - 249 WP_254568984.1 hypothetical protein -
NBH00_RS12800 (NBH00_12800) 2581997..2582392 + 396 WP_254568985.1 hypothetical protein -
NBH00_RS12805 (NBH00_12805) 2582389..2582757 + 369 WP_254568986.1 hypothetical protein -
NBH00_RS12810 (NBH00_12810) 2582754..2583107 + 354 WP_254568987.1 NFACT family protein -
NBH00_RS12815 (NBH00_12815) 2583107..2584447 + 1341 WP_254568988.1 site-specific integrase -
NBH00_RS12820 (NBH00_12820) 2584474..2585880 + 1407 WP_254568989.1 site-specific integrase -
NBH00_RS12825 (NBH00_12825) 2585965..2586198 + 234 WP_254568990.1 hypothetical protein Antitoxin
NBH00_RS12830 (NBH00_12830) 2586198..2586497 + 300 WP_254568991.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NBH00_RS12835 (NBH00_12835) 2587379..2589265 - 1887 WP_254568992.1 MFS transporter -
NBH00_RS12840 (NBH00_12840) 2589398..2589880 - 483 WP_254568993.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 10515.28 Da        Isoelectric Point: 7.1663

>T247712 WP_254568991.1 NZ_CP098502:2586198-2586497 [Paraconexibacter antarcticus]
MRPIHIARLDKTRPVLVLTRELVRAHLRSVTVAPITTTIRGLSTEVPVGPPNGLSGPSVVSCDNITTIPVAALGQQTGVL
LDRQEPALAEAIAMAFDLE

Download         Length: 300 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8404.51 Da        Isoelectric Point: 4.8411

>AT247712 WP_254568990.1 NZ_CP098502:2585965-2586198 [Paraconexibacter antarcticus]
MSKQIAVRLSDELVAFVDRVVESGDERSRAAVVTRALERERRRLAAARDAEILARAGGDPELAGLAEYAARVPLDLD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References