Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1831106..1831721 Replicon chromosome
Accession NZ_CP098500
Organism Serratia symbiotica strain Pl-LLN

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag M5J15_RS09965 Protein ID WP_252747415.1
Coordinates 1831106..1831474 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag M5J15_RS09970 Protein ID WP_252749167.1
Coordinates 1831455..1831721 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5J15_RS09930 (M5J15_09875) 1826341..1826640 + 300 Protein_1979 ATP-binding protein -
M5J15_RS09935 (M5J15_09880) 1826799..1827083 + 285 WP_252747412.1 hypothetical protein -
M5J15_RS09940 (M5J15_09885) 1827128..1827283 + 156 WP_252747413.1 DUF3164 family protein -
M5J15_RS09945 (M5J15_09890) 1827305..1828512 - 1208 Protein_1982 IS256 family transposase -
M5J15_RS09950 (M5J15_09895) 1828594..1829478 + 885 WP_284700538.1 acyltransferase -
M5J15_RS09955 (M5J15_09900) 1829805..1830565 + 761 Protein_1984 DNA adenine methylase -
M5J15_RS09960 (M5J15_09905) 1830673..1830921 + 249 Protein_1985 flavodoxin FldB -
M5J15_RS09965 (M5J15_09910) 1831106..1831474 - 369 WP_252747415.1 protein YgfX Toxin
M5J15_RS09970 (M5J15_09915) 1831455..1831721 - 267 WP_252749167.1 FAD assembly factor SdhE Antitoxin
M5J15_RS09975 (M5J15_09920) 1832054..1833040 + 987 WP_252747416.1 tRNA-modifying protein YgfZ -
M5J15_RS09980 (M5J15_09925) 1833321..1833995 - 675 WP_252747417.1 hemolysin III family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(25-113)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 14796.37 Da        Isoelectric Point: 9.9146

>T247711 WP_252747415.1 NZ_CP098500:c1831474-1831106 [Serratia symbiotica]
VAQWRCDVRISRCTQLFSLLTHGVLVLLILLLFQGIRSQKRLAAVRGELRLLADWRINWHGREWRLVKKPWMPDYGILLT
LHPMEGNKYQRLWLVLDNMEREEWRYLRQRLLYPPVSDDEET

Download         Length: 369 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10328.86 Da        Isoelectric Point: 4.8052

>AT247711 WP_252749167.1 NZ_CP098500:c1831721-1831455 [Serratia symbiotica]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDQLNDTDKALFIRLLECDDPDLFNLLMNHGAPEDSELQRMVALIQSRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References