247705

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 26823..27589 Replicon chromosome
Accession NZ_CP098500
Organism Serratia symbiotica strain Pl-LLN

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag M5J15_RS00200 Protein ID WP_252748134.1
Coordinates 27221..27589 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag M5J15_RS00195 Protein ID WP_252748133.1
Coordinates 26823..27158 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5J15_RS00165 (M5J15_00165) 22180..23208 - 1029 WP_252748129.1 IS21 family transposase -
M5J15_RS00170 (M5J15_00170) 23378..24142 + 765 Protein_33 IS21-like element helper ATPase IstB -
M5J15_RS00175 (M5J15_00175) 24226..24687 + 462 WP_252748130.1 hypothetical protein -
M5J15_RS00180 (M5J15_00180) 24934..25496 + 563 Protein_35 hypothetical protein -
M5J15_RS00185 (M5J15_00185) 25497..26066 + 570 WP_252748131.1 hypothetical protein -
M5J15_RS00190 (M5J15_00190) 26328..26807 + 480 WP_252748132.1 DNA repair protein RadC -
M5J15_RS00195 (M5J15_00195) 26823..27158 + 336 WP_252748133.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
M5J15_RS00200 (M5J15_00200) 27221..27589 + 369 WP_252748134.1 TA system toxin CbtA family protein Toxin
M5J15_RS00205 (M5J15_00205) 27793..28340 - 548 Protein_40 DDE-type integrase/transposase/recombinase -
M5J15_RS00210 (M5J15_00210) 28553..29335 - 783 WP_252748135.1 reverse transcriptase domain-containing protein -
M5J15_RS00215 (M5J15_00215) 29350..29778 - 429 WP_252748136.1 reverse transcriptase domain-containing protein -
M5J15_RS00220 (M5J15_00220) 30381..30641 - 261 WP_252748137.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 106..64179 64073
- inside IScluster/Tn - - 20239..28217 7978


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-110)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13706.67 Da        Isoelectric Point: 5.6193

>T247705 WP_252748134.1 NZ_CP098500:27221-27589 [Serratia symbiotica]
MQTLPVTPKRAAYACPSPVVVWQSMLTYLLEQHYGLALNDTEFSDDAVIHEHIDAGISLADALNFTVEKFDLVRTDRRGF
SCEEQSPFITAIDILRARRATGLMVRMGYQSITSVIRGEKQT

Download         Length: 369 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12340.92 Da        Isoelectric Point: 6.6321

>AT247705 WP_252748133.1 NZ_CP098500:26823-27158 [Serratia symbiotica]
MPSITTPTWGLKRNVTPQLGARLVQEGSRLHFLADRADISGTFSETQIRDLDNAFPQFINHLELMLLSGELNPRHQHCVT
LYRNGLTCEADSLGSHGYAYLAVYPTPQSTA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References