Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3139233..3139882 Replicon chromosome
Accession NZ_CP098480
Organism Acinetobacter sp. C32I

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NDN13_RS14945 Protein ID WP_251116026.1
Coordinates 3139463..3139882 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NDN13_RS14940 Protein ID WP_251116025.1
Coordinates 3139233..3139463 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDN13_RS14930 (NDN13_14925) 3135227..3136384 + 1158 WP_004656677.1 2-methylcitrate synthase -
NDN13_RS14935 (NDN13_14930) 3136384..3139002 + 2619 WP_004656675.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
NDN13_RS14940 (NDN13_14935) 3139233..3139463 + 231 WP_251116025.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NDN13_RS14945 (NDN13_14940) 3139463..3139882 + 420 WP_251116026.1 type II toxin-antitoxin system VapC family toxin Toxin
NDN13_RS14950 (NDN13_14945) 3140013..3140156 + 144 WP_004637424.1 zinc ribbon-containing protein -
NDN13_RS14955 (NDN13_14950) 3140284..3140859 + 576 WP_251118245.1 DUF4126 domain-containing protein -
NDN13_RS14960 (NDN13_14955) 3140902..3141603 + 702 WP_251116027.1 hypothetical protein -
NDN13_RS14965 (NDN13_14960) 3141732..3142433 + 702 WP_251116028.1 hypothetical protein -
NDN13_RS14970 (NDN13_14965) 3142506..3143393 + 888 WP_251116029.1 EamA family transporter -
NDN13_RS14975 (NDN13_14970) 3143964..3144416 + 453 WP_251116030.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15959.19 Da        Isoelectric Point: 6.3313

>T247689 WP_251116026.1 NZ_CP098480:3139463-3139882 [Acinetobacter sp. C32I]
MQTQYLLDTNICIYISKHQPESVRQHFEKHLPNRNILISVITLGELRFGAEKSQSKEKALKVIDEFISMIQVAELDEDVA
DHYAQIRQALSSKGQIIGSNDLWLAAHARANNWVMVTNNEKEFLRVDGLRVENWVSTPL

Download         Length: 420 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9023.23 Da        Isoelectric Point: 4.5463

>AT247689 WP_251116025.1 NZ_CP098480:3139233-3139463 [Acinetobacter sp. C32I]
MSTAKVFMTGRSQAIRLPKEFRFEGTEVEIFRRGDEVILREKPITAERLFNVLAQMPDDFYAEERVDQPPQEREEF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References