Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 447493..448132 Replicon chromosome
Accession NZ_CP098479
Organism Acinetobacter sp. C26G

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NDN12_RS02165 Protein ID WP_251111469.1
Coordinates 447743..448132 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N8XN48
Locus tag NDN12_RS02160 Protein ID WP_004804137.1
Coordinates 447493..447750 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDN12_RS02140 (NDN12_02140) 443114..443632 + 519 WP_251110639.1 tetratricopeptide repeat protein -
NDN12_RS02145 (NDN12_02145) 443966..445456 + 1491 WP_004804131.1 NAD(P)/FAD-dependent oxidoreductase -
NDN12_RS02150 (NDN12_02150) 445583..446083 + 501 WP_251110640.1 DUF2059 domain-containing protein -
NDN12_RS02155 (NDN12_02155) 446133..447305 - 1173 WP_167248702.1 acyl-CoA dehydrogenase family protein -
NDN12_RS02160 (NDN12_02160) 447493..447750 + 258 WP_004804137.1 succinate dehydrogenase assembly factor 2 Antitoxin
NDN12_RS02165 (NDN12_02165) 447743..448132 + 390 WP_251111469.1 hypothetical protein Toxin
NDN12_RS02170 (NDN12_02170) 448340..448546 + 207 WP_167248705.1 hypothetical protein -
NDN12_RS02175 (NDN12_02175) 448906..450021 + 1116 WP_251110641.1 hypothetical protein -
NDN12_RS02180 (NDN12_02180) 450097..450678 + 582 WP_167248707.1 rhombosortase -
NDN12_RS02185 (NDN12_02185) 450858..453062 + 2205 WP_167248708.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.70 Da        Isoelectric Point: 9.7340

>T247687 WP_251111469.1 NZ_CP098479:447743-448132 [Acinetobacter sp. C26G]
MANGVFELQRSRFAMVLQLLIFIAILSLTYSLLALWIWLLCFCMMGAAWILFLKQPQIKRFEYLDHQECSFEFYDPELKI
QRRKIVKILDHKFYIALYFSHSNQRTCIIWWDQLSHSQWQKLKLRAKLA

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10101.54 Da        Isoelectric Point: 4.5935

>AT247687 WP_004804137.1 NZ_CP098479:447493-447750 [Acinetobacter sp. C26G]
MSDEMTLEERKVVYRARRGLKEIDVYFDPYVKNHYLTADIAEKALFAELVDQEDPDLLDWFMEVGEPPRAELKDFILKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N8XN48

References