Detailed information of TA system TA247662

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3287106..3288826
• Replicon: chromosome
• Accession: NZ_CP098455
• Organism: Spongiibacter taiwanensis strain SPT1

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: NCG89_RS14915
• Protein ID: WP_251087358.1
• Coordinates: 3287106..3287759 (+)
• Length: 218 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: NCG89_RS14920
• Protein ID: WP_251087359.1
• Coordinates: 3287759..3288826 (+)
• Length: 356 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NCG89_RS14900 (NCG89_14900)	3282426..3282665	+	240	WP_251087355.1	transcription factor	-
NCG89_RS14905 (NCG89_14905)	3282769..3285174	+	2406	WP_251087356.1	type I restriction-modification system subunit M	-
NCG89_RS14910 (NCG89_14910)	3285174..3287099	+	1926	WP_251087357.1	restriction endonuclease subunit S	-
NCG89_RS14915 (NCG89_14915)	3287106..3287759	+	654	WP_251087358.1	DUF4433 domain-containing protein	Toxin
NCG89_RS14920 (NCG89_14920)	3287759..3288826	+	1068	WP_251087359.1	macro domain-containing protein	Antitoxin
NCG89_RS14925 (NCG89_14925)	3288869..3291958	+	3090	WP_251087360.1	type I restriction endonuclease subunit R	-
NCG89_RS14930 (NCG89_14930)	3291958..3292671	+	714	WP_251087361.1	SprT family zinc-dependent metalloprotease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (17-217)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 218 a.a.
• Molecular weight: 24874.22 Da
• Isoelectric Point: 7.5058

>T247662 WP_251087358.1 NZ_CP098455:3287106-3287759 [Spongiibacter taiwanensis]
MAYDYSATLNPQKALIWRIVHRDNIPWILDNGLHSGNSTVQSPGWVPIGNPELTDKRATHAVPAGPGGYLNDYVPFYFTP
FSPMMKNIHSGRAGVHRRRNDEIVILVSSLYKVQNLGLPFVFSDGHAYYAWSNFYTDLADLDKIDWPIIQARDFKRDPDD
PAKFERYQAEALIHQHCPVAALEGMICYTAKTQAQLDNWLQARQIRMPVYARSGWYF

Nucleotide

• Length: 654 bp

Antitoxin

Protein

• Length: 356 a.a.
• Molecular weight: 39930.10 Da
• Isoelectric Point: 5.3357

>AT247662 WP_251087359.1 NZ_CP098455:3287759-3288826 [Spongiibacter taiwanensis]
MITYLQGNLLDAEVEALVNTVNTVGVMGKGIALMFKERFPQNMQEYAQACKAGEVQTGRMFVTKTGELMGPKWVVNFPTK
QHWKAKSKMEWIESGLEDLRRFIEENRLQSIAIPPLGAGNGGLNWQEVKPLVERALGDLEGVNILVFEPTAKYQNVSKKS
GVNTLTPARALVAELVRRYWILGMECSLLEIQKLAWFLQRVIDAKGLDNQLKLDFEANYYGPYANNLTHLLNALDGSYLK
ADKRIPDSQPLDVIAFNDNKKDFVEAYLATEAKAYLPTLEQTSQLIDGFESPFGMELLSTVDWLVVKDNCELALGSIKEG
MARWPAGKQWAERKLNLFDDKSLQIAIDRLKAVPL

Nucleotide

• Length: 1068 bp