Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1989585..1989730 Replicon chromosome
Accession NZ_CP098355
Organism Klebsiella pneumoniae strain 13001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1989621..1989723 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1989585..1989730 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB672_RS09835 (NB672_09835) 1984715..1986775 + 2061 WP_004151449.1 oligopeptidase B -
NB672_RS09840 (NB672_09840) 1986779..1987438 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB672_RS09845 (NB672_09845) 1987517..1987747 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB672_RS09850 (NB672_09850) 1987860..1988234 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB672_RS09855 (NB672_09855) 1988238..1989107 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB672_RS09860 (NB672_09860) 1989124..1989462 + 339 WP_002911404.1 YebY family protein -
- 1989585..1989730 - 146 - - Antitoxin
- 1989621..1989723 + 103 - - Toxin
NB672_RS09865 (NB672_09865) 1990098..1990241 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB672_RS09870 (NB672_09870) 1990346..1991314 - 969 WP_004151446.1 VirK/YbjX family protein -
NB672_RS09875 (NB672_09875) 1991471..1992124 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB672_RS09880 (NB672_09880) 1992121..1992312 - 192 WP_002911395.1 YebW family protein -
NB672_RS09885 (NB672_09885) 1992410..1992649 - 240 WP_002911393.1 YebV family protein -
NB672_RS09890 (NB672_09890) 1992765..1994198 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247569 NZ_CP098355:1989621-1989723 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247569 NZ_CP098355:c1989730-1989585 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References